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WormBase Tree Display for Interaction: WBInteraction000524139

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Name Class

WBInteraction000524139Interaction_typeGeneticOpposing_epistasis
GI_module_oneTrans_phenotypic
GI_module_twoMasking
InteractorInteractor_overlapping_geneWBGene00002992Interactor_typeAffected
TransgeneWBTransgene00004656
WBGene00001174Interactor_typeEffector
Variation_interactorWBVar00089847Interactor_typeEffector
Interaction_summaryOverexpression of the EGF domain of LIN-3 by a heat shock promoter (which normally results in a P11 to P12 cell fate transformation) in the egl-5(n945) mutant background (which normally results in the opposite, P12 to P11 cell fate transformation) resulted entirely (100% penetrance) in the egl-5(n945) P12 to P11 cell fate transformation phenotype, suggesting that egl-5(n945) is epistatic to LIN-3 EGF overexpression.
Detection_methodTransgene
ThroughputLow_throughput
Interaction_phenotypeWBPhenotype:0000414
WBProcessWBbiopr:00000024
PaperWBPaper00003135
RemarkTable 1B