WormBase Tree Display for Interaction: WBInteraction000523870
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| WBInteraction000523870 | Interaction_type | Genetic | Mutual_enhancement | ||
|---|---|---|---|---|---|
| GI_module_one | Cis_phenotypic | ||||
| GI_module_two | Enhancing | ||||
| Interactor | Interactor_overlapping_gene | WBGene00004457 | Interactor_type | Non_directional | |
| WBGene00006363 | Interactor_type | Non_directional | |||
| Variation_interactor | WBVar00088149 | Interactor_type | Non_directional | ||
| WBVar00088157 | Interactor_type | Non_directional | |||
| Interaction_summary | SNB-1::GFP puncta were barely detectable in the presumed presynaptic regions along the nerve processes. Examination of several synaptic markers in other types of neurons revealed a similar reduction in synapse number and abnormal synapse morphology. The morphological defects were observed from young larvae through adult stages. | ||||
| Double mutants displayed dramatically reduced numbers of synapses in cholinergic and GABAergic motor neurons. Further, the few remaining synapses contained very few synaptic vesicles that were scattered near the presynaptic dense projections. | |||||
| Throughput | Low_throughput | ||||
| Interaction_phenotype | WBPhenotype:0001321 | ||||
| WBPhenotype:0000625 | |||||
| WBProcess | WBbiopr:00000117 | ||||
| Paper | WBPaper00045690 |
