WormBase Tree Display for Gene: WBGene00006363
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| WBGene00006363 | Evidence | Paper_evidence | WBPaper00005543 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SMap | S_parent | Sequence | F35D2 | ||||||
| Identity | Version | 1 | |||||||
| Name | CGC_name | syd-1 | Person_evidence | WBPerson105 | |||||
| WBPerson293 | |||||||||
| Sequence_name | F35D2.5 | ||||||||
| Molecular_name | F35D2.5a | ||||||||
| F35D2.5a.1 | |||||||||
| CE33391 | |||||||||
| F35D2.5c | |||||||||
| CE33392 | |||||||||
| F35D2.5c.1 | |||||||||
| F35D2.5c.2 | |||||||||
| Other_name | CELE_F35D2.5 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | syd-1 | ||||||||
| DB_info | Database | AceView | gene | 2H876 | |||||
| WormQTL | gene | WBGene00006363 | |||||||
| WormFlux | gene | WBGene00006363 | |||||||
| NDB | locus_tag | CELE_F35D2.5 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00006363|UniProtKB=Q86NH1 | |||||||
| family | PTHR46150 | ||||||||
| NCBI | gene | 174230 | |||||||
| RefSeq | protein | NM_001026975.4 | |||||||
| NM_001383891.2 | |||||||||
| SwissProt | UniProtAcc | Q86NH1 | |||||||
| TREEFAM | TREEFAM_ID | TF323458 | |||||||
| UniProt_GCRP | UniProtAcc | Q86NH1 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:40 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | syd | ||||||||
| Allele (120) | |||||||||
| Strain | WBStrain00032087 | ||||||||
| WBStrain00037967 | |||||||||
| WBStrain00005369 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (23) | |||||||||
| Ortholog (39) | |||||||||
| Paralog | WBGene00015267 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| Structured_description | Concise_description | syd-1 encodes a protein that contains a Rho-GTPase-like activating domain as well as PDZ and C2 domains; during neuronal development, SYD-1 is required cell autonomously to positively regulate synaptogenesis; in regulating synapse development, SYD-1 functions as a positive regulator of SYD-2/liprin through direct interaction with ELKS-1, a pre-synaptic protein also required for synapse development; in turn, SYD-1 activity is regulated by RSY-1, a negative regulator of synaptogenesis, with which it also interacts physically; SYD-1 is expressed in neurons and localizes to presynaptic regions. | Paper_evidence | WBPaper00005543 | |||||
| WBPaper00028808 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 08 Mar 2010 00:00:00 | ||||||||
| Automated_description | Enables GTPase activator activity; Roundabout binding activity; and small GTPase binding activity. Involved in cell projection organization; cellular localization; and locomotion. Located in presynaptic membrane. Expressed in nerve ring and neurons. Is an ortholog of human SYDE2 (synapse defective Rho GTPase homolog 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F35D2.5a | |||||||
| F35D2.5c | |||||||||
| Corresponding_CDS_history | F35D2.5:wp84 | ||||||||
| F35D2.5:wp92 | |||||||||
| F35D2.5b:wp93 | |||||||||
| F35D2.5b:wp274 | |||||||||
| Corresponding_transcript | F35D2.5a.1 | ||||||||
| F35D2.5c.1 | |||||||||
| F35D2.5c.2 | |||||||||
| Other_sequence (15) | |||||||||
| Associated_feature (15) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00082910 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00046330 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00031774 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00014326 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern (11) | |||||||||
| Drives_construct | WBCnstr00000711 | ||||||||
| WBCnstr00000728 | |||||||||
| WBCnstr00010752 | |||||||||
| WBCnstr00034391 | |||||||||
| Construct_product | WBCnstr00000728 | ||||||||
| WBCnstr00007017 | |||||||||
| WBCnstr00010752 | |||||||||
| WBCnstr00010753 | |||||||||
| WBCnstr00012368 | |||||||||
| WBCnstr00012375 | |||||||||
| WBCnstr00018295 | |||||||||
| WBCnstr00021865 | |||||||||
| WBCnstr00034391 | |||||||||
| WBCnstr00038079 | |||||||||
| Antibody | WBAntibody00000569 | ||||||||
| Microarray_results (33) | |||||||||
| Expression_cluster (201) | |||||||||
| Interaction (51) | |||||||||
| Map_info | Map | II | Position | 0.504817 | Error | 4.2e-05 | |||
| Positive | Positive_clone | F35D2 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4188 | |||||||
| 4715 | |||||||||
| 4733 | |||||||||
| 5534 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (52) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
