WormBase Tree Display for Interaction: WBInteraction000520876
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| WBInteraction000520876 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00004932 | Interactor_type | Trans_regulated | |
| Transgene | WBTransgene00001052 | ||||
| Construct | WBCnstr00001043 | ||||
| WBGene00003931 | Interactor_type | Trans_regulator | |||
| Interaction_summary | Expression of sod-3::gfp reporter was increased in multiple tissues, most notably in the intestine, in 3-day-old animals subjected to pat-4/ILK RNAi from day 1 of adulthood. Consistently, we found the mRNA levels of sod-3 and hsp-16.2 significantly upregulated upon reduction of pat-4/ILK. Thus, inhibition of pat- 4/ILK induced expression of genes typically upregulated in response to environmental stressors, consistent with the mobilization of a stress response. | ||||
| Detection_method | Construct | ||||
| Reporter_gene | [sod-3::gfp] | ||||
| Transgene | |||||
| Regulation_level | Transcriptional | ||||
| Interaction_RNAi | WBRNAi00094406 | ||||
| Paper | WBPaper00044579 |
