WormBase Tree Display for Interaction: WBInteraction000519436
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| WBInteraction000519436 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00002187 | Interactor_type | Trans_regulator | |
| WBGene00011869 | Interactor_type | Trans_regulated | |||
| Other_interactor | fasting | Interactor_type | Trans_regulator | ||
| Variation_interactor | WBVar00088251 | Interactor_type | Trans_regulator | ||
| Interaction_summary | While daf-16 targeting gene dod-6 mRNA levels were markedly increased in response to fasting in wild-type worms, their increases were significantly suppressed in the loss-of-function mutant of kgb-1 (kgb-1(km21)), suggesting the possibility that KGB-1 signaling is required for the fasting-induced activation of DAF- 16. | ||||
| Detection_method | RT_PCR | ||||
| Regulation_level | Transcriptional | ||||
| Paper | WBPaper00041960 |
