WormBase Tree Display for Interaction: WBInteraction000518674
expand all nodes | collapse all nodes | view schema
| WBInteraction000518674 | Interaction_type | Regulatory | Change_of_expression_level | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00011737 | Interactor_type | Trans_regulated | |
| Transgene | WBTransgene00007081 | ||||
| Construct | WBCnstr00006906 | ||||
| WBGene00021546 | Interactor_type | Trans_regulator | |||
| Variation_interactor | WBVar01429652 | Interactor_type | Trans_regulator | ||
| Interaction_summary | Autophagy substrates SEPA-1 and T12G3.1 (the C. elegans homolog of mammalian p62) were cleared during embryogenesis in wild type but persisted in late-stage qx42 mutant embryos and overlapped with NUC-1::mCherry, indicating defective autolysosomal degradation. | ||||
| Detection_method | Construct | ||||
| Reporter_gene | [T12G3.1::gfp] | ||||
| Transgene | |||||
| Regulation_level | Post_translational | ||||
| Regulation_result | Negative_regulate | Life_stage | WBls:0000003 | ||
| Subcellular_localization | lysosome | ||||
| Paper | WBPaper00041321 |
