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WormBase Tree Display for Interaction: WBInteraction000502206

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Name Class

WBInteraction000502206Interaction_typeRegulatoryChange_of_expression_level
InteractorInteractor_overlapping_geneWBGene00001185Interactor_typeTrans_regulated
Expr_patternExpr2354
TransgeneWBTransgene00000097
ConstructWBCnstr00000097
WBGene00002990Interactor_typeTrans_regulator
Variation_interactorWBVar00248951Interactor_typeTrans_regulator
Interaction_summaryIn hermaphrodites homozygous for mutations that reduce or eliminate lin-1 activity, egl-17::gfp expression is either much lower than in wild type or undetectable. Thus, lin-1 is required positively for proper early expression of the egl-17::gfp marker. lin-1(lf) had no effect on the late expression of egl-17::gfp in the descendents of VPCs adopting the 2 cell fate. 73% of lin-1(RNAi) animals showed reduced or undetectable levels of egl-17::gfp in P6.p.
Detection_methodConstruct
Reporter_gene[egl-17::gfp]
Transgene
Regulation_levelTranscriptional
Regulation_resultPositive_regulateAnatomy_termWBbt:0006987
WBbt:0006989
WBbt:0006990
WBbt:0006988
WBbt:0008125
Interaction_RNAiWBRNAi00064251
PaperWBPaper00026783