WormBase Tree Display for Interaction: WBInteraction000502137
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| WBInteraction000502137 | Interaction_type | Regulatory | Change_of_localization | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00003885 | Interactor_type | Trans_regulator | |
| WBGene00001129 | Interactor_type | Trans_regulated | |||
| Expr_pattern | Expr3733 | ||||
| Variation_interactor | WBVar00095130 | Interactor_type | Trans_regulator | ||
| Interaction_summary | In the wild-type, C27H5.7a::GFP localizes at the transition zones and along ciliary axonemes, C27H5.7a::GFP accumulates at transition zones in osm-5 mutants. | ||||
| Detection_method | Reporter_gene | [C27H5.7a::gfp] translational fusion. | |||
| Regulation_result | Positive_regulate | Anatomy_term | WBbt:0006816 | ||
| Subcellular_localization | GFP-tagged C27H5.7a associate with ciliary axonemes in both head (amphids, labials) and tail (phasmids) neurons, with relatively little localization to cell bodies, axons, or dendrites. In addition, C27H5.7a::GFP localizes to the transition zones (basal bodies at the base of cilia). | ||||
| Paper | WBPaper00026601 | ||||
| Remark | The dependence of C27H5.7a on osm-5 for its normal localization and motility strongly suggests that C27H5.7a is part of the motor-IFT particle-cargo complex. |
