WormBase Tree Display for Interaction: WBInteraction000501765
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| WBInteraction000501765 | Interaction_type | Regulatory | Change_of_localization | ||
|---|---|---|---|---|---|
| Interactor | Interactor_overlapping_gene | WBGene00000148 | Interactor_type | Trans_regulated | |
| Expr_pattern | Expr1036 | ||||
| Antibody | WBAntibody00000288 | ||||
| WBGene00000147 | Interactor_type | Trans_regulator | |||
| WBGene00001985 | Interactor_type | Trans_regulator | |||
| WBGene00004769 | Interactor_type | Trans_regulator | |||
| Variation_interactor | WBVar00266480 | Interactor_type | Trans_regulator | ||
| WBVar00275487 | Interactor_type | Trans_regulator | |||
| Interaction_summary | In aph-1 mutant embryos, APH-2 was not detectable on the cell surface, and was instead prominent in the cytoplasm of all four cells, where it was concentrated around the nucleus in a pattern characteristic of the endoplasmic reticulum. Presenilin-deficient embryos showed an abnormal accumulation of APH-2 around the nucleus. | ||||
| Detection_method | Antibody | ||||
| Regulation_level | Post_translational | ||||
| Regulation_result | Positive_regulate | Life_stage | WBls:0000008 | ||
| Interaction_RNAi | WBRNAi00077180 | ||||
| Paper | WBPaper00005082 |
