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WormBase Tree Display for Gene: WBGene00045192

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Name Class

WBGene00045192SMapS_parentSequenceK04G2
IdentityVersion2
NameCGC_nameaho-3Paper_evidenceWBPaper00025146
WBPaper00040997
Sequence_nameK04G2.2
Molecular_nameK04G2.2
K04G2.2.1
CE37533
Other_nameCELE_K04G2.2Accession_evidenceNDBBX284601
Public_nameaho-3
DB_infoDatabaseWormFluxgeneWBGene00045192
NDBlocus_tagCELE_K04G2.2
PanthergeneCAEEL|WormBase=WBGene00045192|UniProtKB=Q21221
familyPTHR12277
NCBIgene172585
RefSeqproteinNM_059809.8
KEGGKEGG_id3.1.2.22
NemaPathKEGG_id3.1.2.22
SwissProtUniProtAccQ21221
TREEFAMTREEFAM_IDTF314365
UniProt_GCRPUniProtAccQ21221
SpeciesCaenorhabditis elegans
HistoryVersion_change104 Dec 2006 15:24:19WBPerson1847EventCreated
227 Apr 2012 16:35:24WBPerson2970EventAcquires_mergeWBGene00010561
Name_changeSequence_nameK04G2.2
Acquires_mergeWBGene00010561
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classaho
Allele (20)
StrainWBStrain00022016
RNASeq_FPKM (74)
GO_annotation (18)
Ortholog (62)
ParalogWBGene00008222Caenorhabditis elegansFrom_analysisPanther
WBGene00008497Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00008498Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00018131Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00022140Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
WBGene00022393Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
WBGene00044003Caenorhabditis elegansFrom_analysisTreeFam
Panther
WormBase-Compara
Structured_descriptionConcise_descriptionaho-3 encodes a hydrolase; aho-3 is required for temperature preference, a learning-like behavior associating feeding conditions with temperatures; while normal C. elegans thermotax away from those temperatures at which they have been starved for 1 hour, aho-3(nj15) mutants fail to show this connection of temperature preference to recent starvation; although aho-3(nj15) mutants fail to show correct temperature preferences at 25 deg. C., they are phenotypically normal at 17 deg. C.; aho-3(nj15) mutants display normal chemotaxis to sodium, avoidance of copper, and olfaction, but are defective in male mating.Paper_evidenceWBPaper00025146
WBPaper00040997
Curator_confirmedWBPerson1843
WBPerson567
Date_last_updated23 Apr 2012 00:00:00
Automated_descriptionPredicted to enable palmitoyl-(protein) hydrolase activity. Involved in associative learning and behavioral response to starvation. Located in cytoplasmic vesicle and sensory dendrite. Expressed in AIY; amphid neurons; and serotonergic neurons. Is an ortholog of human ABHD17A (abhydrolase domain containing 17A, depalmitoylase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSK04G2.2
Corresponding_CDS_historyK04G2.2:wp132
Corresponding_transcriptK04G2.2.1
Other_sequence (48)
Associated_feature (11)
Experimental_infoRNAi_resultWBRNAi00049935Inferred_automaticallyRNAi_primary
WBRNAi00003916Inferred_automaticallyRNAi_primary
WBRNAi00116581Inferred_automaticallyRNAi_primary
Expr_patternExpr10076
Expr10648
Expr13917
Expr1040350
Expr1153640
Expr2009270
Expr2027507
Drives_constructWBCnstr00015048
WBCnstr00023304
WBCnstr00040361
Construct_productWBCnstr00023304
Microarray_results (20)
Expression_cluster (125)
Map_infoMapIPosition2.42756
PositivePositive_cloneK04G2Inferred_automaticallyFrom sequence, transcript, pseudogene data
ReferenceWBPaper00025146
WBPaper00030204
WBPaper00034183
WBPaper00036590
WBPaper00038491
WBPaper00040997
WBPaper00052802
WBPaper00055090
WBPaper00064339
MethodGene