WormBase Tree Display for Gene: WBGene00044094
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| WBGene00044094 | SMap | S_parent | Sequence | ZK265 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | fitm-2 | Person_evidence | WBPerson205 | |||||
| Sequence_name | ZK265.9 | ||||||||
| Molecular_name | ZK265.9 | ||||||||
| ZK265.9.1 | |||||||||
| CE38132 | |||||||||
| Other_name | CELE_ZK265.9 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | fitm-2 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 27 Jan 2005 14:40:44 | WBPerson1846 | Event | Created | |||
| 2 | 09 Jan 2015 16:33:20 | WBPerson2970 | Name_change | CGC_name | fitm-2 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | fitm | ||||||||
| Allele (23) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (16) | |||||||||
| Ortholog (42) | |||||||||
| Structured_description | Concise_description | fitm-2 encodes an ortholog of FIT1 and FIT2, membrane proteins of the endoplasmic reticulum that both induce, and are required for, lipid droplet accumulation; more distantly, FITM-2 is orthologous to budding yeast Scs3p and Yft2p. | Paper_evidence | WBPaper00031361 | |||||
| WBPaper00031452 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 12 Jan 2015 00:00:00 | ||||||||
| Automated_description | Predicted to enable acyl-coenzyme A diphosphatase activity. Involved in lipid droplet formation. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in Siddiqi syndrome. Is an ortholog of human FITM2 (fat storage inducing transmembrane protein 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0081273 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:16135) | ||||
| Molecular_info | Corresponding_CDS | ZK265.9 | |||||||
| Corresponding_transcript | ZK265.9.1 | ||||||||
| Other_sequence (20) | |||||||||
| Associated_feature | WBsf649374 | ||||||||
| WBsf984384 | |||||||||
| WBsf1010205 | |||||||||
| WBsf219886 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00004921 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00059318 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1028705 | ||||||||
| Expr1040185 | |||||||||
| Expr1162751 | |||||||||
| Expr2011794 | |||||||||
| Expr2030032 | |||||||||
| Drives_construct | WBCnstr00023764 | ||||||||
| Construct_product | WBCnstr00023764 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (113) | |||||||||
| Interaction | WBInteraction000585770 | ||||||||
| Map_info | Map | I | Position | 2.70337 | |||||
| Positive | Positive_clone | ZK265 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00048723 | |||||||||
| WBPaper00049815 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
