WormBase Tree Display for Gene: WBGene00022642
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WBGene00022642 | SMap | S_parent | Sequence | ZK6 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | lipl-5 | Person_evidence | WBPerson3759 | |||||
WBPerson7490 | |||||||||
WBPerson545 | |||||||||
Sequence_name | ZK6.7 | ||||||||
Molecular_name | ZK6.7a | ||||||||
ZK6.7a.1 | |||||||||
CE18444 | |||||||||
ZK6.7c | |||||||||
CE50798 | |||||||||
ZK6.7d | |||||||||
CE50743 | |||||||||
ZK6.7b | |||||||||
ZK6.7c.1 | |||||||||
ZK6.7d.1 | |||||||||
Other_name | CELE_ZK6.7 | Accession_evidence | NDB | BX284605 | |||||
Public_name | lipl-5 | ||||||||
DB_info | Database (13) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 28 May 2004 13:31:06 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
2 | 19 Jul 2010 13:43:13 | WBPerson2970 | Name_change | CGC_name | lipl-5 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | lipl | ||||||||
Allele (47) | |||||||||
Strain | WBStrain00033248 | ||||||||
WBStrain00037811 | |||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (14) | |||||||||
Ortholog (66) | |||||||||
Paralog (7) | |||||||||
Structured_description | Concise_description | lipl-5 encodes a lipase; lipl-5 is expressed in the intestine and its expression is negatively regulated in well-fed animals by MXL-3; lipl-5 expression is induced upon bacterial infection. | Paper_evidence | WBPaper00005382 | |||||
WBPaper00042295 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 19 Jun 2013 00:00:00 | ||||||||
Automated_description | Predicted to enable hydrolase activity, acting on ester bonds. Involved in defense response to Gram-negative bacterium; lipid homeostasis; and triglyceride catabolic process. Located in lysosome. Expressed in coelomocyte and intestine. Human ortholog(s) of this gene implicated in Wolman disease; autosomal recessive congenital ichthyosis 8; and cholesterol ester storage disease. Is an ortholog of several human genes including LIPA (lipase A, lysosomal acid type); LIPF (lipase F, gastric type); and LIPJ (lipase family member J). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0080217 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6617) | ||||
DOID:14502 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6617) | ||||||
DOID:14497 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:6617) | ||||||
DOID:0060717 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:23452) | ||||||
Molecular_info (5) | |||||||||
Experimental_info | RNAi_result (12) | ||||||||
Expr_pattern | Expr1967 | ||||||||
Expr14545 | |||||||||
Expr14546 | |||||||||
Expr1010508 | |||||||||
Expr1162960 | |||||||||
Expr2013207 | |||||||||
Expr2031439 | |||||||||
Drives_construct | WBCnstr00041084 | ||||||||
Construct_product | WBCnstr00041084 | ||||||||
Microarray_results (23) | |||||||||
Expression_cluster (289) | |||||||||
Interaction (38) | |||||||||
WBProcess | WBbiopr:00000039 | ||||||||
Map_info | Map | V | Position | -20 | |||||
Positive | Positive_clone | ZK6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference (12) | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |