WormBase Tree Display for Gene: WBGene00022269

WBGene00022269 SMap: S_parent: Sequence: Y73E7A
  Identity: Version: 2
    Name: CGC_name: aatf-1 Person_evidence: WBPerson31189
            WBPerson124
      Sequence_name: Y73E7A.2
      Molecular_name: Y73E7A.2
        Y73E7A.2.1
        CE32277
      Other_name: CELE_Y73E7A.2 Accession_evidence: NDB BX284601
      Public_name: aatf-1
    DB_info: Database: AceView gene 1C79
        WormQTL gene WBGene00022269
        WormFlux gene WBGene00022269
        NDB locus_tag CELE_Y73E7A.2
        Panther gene CAEEL|WormBase=WBGene00022269|UniProtKB=Q9GUM5
          family PTHR15565
        NCBI gene 171723
        RefSeq protein NM_058469.8
        TREEFAM TREEFAM_ID TF324341
        TrEMBL UniProtAcc Q9GUM5
        UniProt_GCRP UniProtAcc Q9GUM5
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:05 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 20 May 2019 14:10:26 WBPerson1983 Name_change: CGC_name: aatf-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: aatf
    Allele (132)
    Strain: WBStrain00050297
    RNASeq_FPKM (74)
    GO_annotation: 00092560
      00092561
      00126418
    Ortholog (17)
    Structured_description: Concise_description: Y73E7A.2 encodes a protein with similarity to the vertebrate apoptosis antagonizing transcription factor (AATF); in C. elegans, a deletion mutation in Y73E7A.2, tm5125, has been reported to result in lethality and sterility; studies in vertebrates indicate that AATF binds RNA polymerase II and plays a role in transcriptional regulation, cell-cycle progression, checkpoint control, and apoptosis via regulation of p53 expression. Paper_evidence: WBPaper00040074
          Curator_confirmed: WBPerson1843
          Date_last_updated: 11 Aug 2011 00:00:00
      Automated_description: Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleolus. Is an ortholog of human AATF (apoptosis antagonizing transcription factor). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: Y73E7A.2
    Corresponding_CDS_history: Y73E7A.2:wp88
    Corresponding_transcript: Y73E7A.2.1
    Other_sequence (17)
    Associated_feature: WBsf217225
      WBsf217226
    Transcription_factor: WBTranscriptionFactor000633
  Experimental_info: RNAi_result: WBRNAi00116559 Inferred_automatically: RNAi_primary
      WBRNAi00058363 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1014646
      Expr1039822
      Expr1161783
      Expr2008373
      Expr2026615
    Microarray_results (17)
    Expression_cluster (83)
    Interaction (146)
  Map_info: Map: I Position: -14.0012
    Positive: Positive_clone: Y73E7A Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00027309
    WBPaper00038491
    WBPaper00055090
    WBPaper00060602
    WBPaper00064339
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene