WormBase Tree Display for Gene: WBGene00022178

WBGene00022178 SMap: S_parent: Sequence: Y71H2AM
  Identity: Version: 2
    Name: CGC_name: cest-25 Person_evidence: WBPerson36909
            WBPerson7188
      Sequence_name: Y71H2AM.13
      Molecular_name: Y71H2AM.13
        Y71H2AM.13.1
        CE22953
      Other_name: CELE_Y71H2AM.13 Accession_evidence: NDB BX284603
      Public_name: cest-25
    DB_info: Database: AceView gene 3D824
        WormQTL gene WBGene00022178
        WormFlux gene WBGene00022178
        NDB locus_tag CELE_Y71H2AM.13
        Panther gene CAEEL|WormBase=WBGene00022178|UniProtKB=Q9BL43
          family PTHR44590
        NCBI gene 175390
        RefSeq protein NM_065208.8
        TrEMBL UniProtAcc Q9BL43
        UniProt_GCRP UniProtAcc Q9BL43
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:05 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 20 May 2019 14:10:26 WBPerson1983 Name_change: CGC_name: cest-25
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cest
    Allele: WBVar00392596
      WBVar00392597
      WBVar01396288
      WBVar01627849
      WBVar01627850
      WBVar00233399
      WBVar01627851
      WBVar01500082
      WBVar01655899
      WBVar01655900
      WBVar01655901
      WBVar01655902
      WBVar01655903
      WBVar01655904
      WBVar01655905
      WBVar00235992
      WBVar02100220
      WBVar01498832
      WBVar02124887
      WBVar01951856
      WBVar01951857
      WBVar00050958
      WBVar00050963
      WBVar00050968
      WBVar02121586
      WBVar00050973
      WBVar01444550
      WBVar01444551
      WBVar01444552
      WBVar01444553
      WBVar01565839
      WBVar01444554
      WBVar01565840
      WBVar02120676
      WBVar00811527
      WBVar01444555
      WBVar00811528
      WBVar01444556
      WBVar01444557
      WBVar00811529
      WBVar00811530
      WBVar01444558
      WBVar00811531
      WBVar01444559
      WBVar00811532
      WBVar01444560
      WBVar01444561
      WBVar00811533
      WBVar00811534
      WBVar01444563
      WBVar00811535
      WBVar00811536
      WBVar00811537
      WBVar00811538
      WBVar00811539
      WBVar00811540
      WBVar00811541
      WBVar00811542
      WBVar00811543
      WBVar00811544
      WBVar00031391
      WBVar00257905
      WBVar00811545
      WBVar00811546
      WBVar00811547
      WBVar00031396
      WBVar01999266
      WBVar00811548
      WBVar00811549
      WBVar02099535
      WBVar00811550
      WBVar00561925
      WBVar00811551
      WBVar00811552
      WBVar00031406
      WBVar00811553
      WBVar00811554
      WBVar00811555
      WBVar00811556
      WBVar00811557
      WBVar02095862
      WBVar00811558
      WBVar00031416
      WBVar00811559
      WBVar00811560
      WBVar00031426
      WBVar00264182
      WBVar01938216
      WBVar01938217
      WBVar01328647
      WBVar01328649
      WBVar01918555
      WBVar01328651
      WBVar01328652
      WBVar02096806
      WBVar01408010
      WBVar01408012
      WBVar01643537
      WBVar01643538
      WBVar01491017
      WBVar01643539
      WBVar01491018
      WBVar01643540
      WBVar01643541
      WBVar01643542
      WBVar01962317
      WBVar01643543
      WBVar02074125
      WBVar00097694
      WBVar01913042
      WBVar01913043
      WBVar01913044
      WBVar01913045
      WBVar01260196
      WBVar00392586
      WBVar01260198
      WBVar00392587
      WBVar00392588
      WBVar01260199
      WBVar00392589
      WBVar01260201
      WBVar00392590
      WBVar01260202
      WBVar01260203
      WBVar00392591
      WBVar00392592
      WBVar01260204
      WBVar00392593
      WBVar01260208
      WBVar00392594
      WBVar00392595
      WBVar01541066
    RNASeq_FPKM (74)
    Ortholog (34)
    Paralog (41)
    Structured_description: Automated_description: Enriched in several structures, including dopaminergic neurons; excretory cell; mc2; mechanosensory neurons; and somatic gonad precursor based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by eleven chemicals including D-glucose; Sodium Chloride; and Rifampin based on RNA-seq; microarray; and proteomic studies. Human ortholog(s) of this gene implicated in colorectal cancer; hepatocellular carcinoma; and stomach cancer. Human CES1 enables carboxylesterase activity and sterol esterase activity. Is predicted to encode a protein with the following domains: Alpha/Beta hydrolase fold; Carboxylesterase, type B; and Carboxylesterase family. Is an ortholog of human CES1 (carboxylesterase 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:9256 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1863)
      DOID:3119 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1863)
      DOID:10534 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1863)
      DOID:684 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:1863)
  Molecular_info: Corresponding_CDS: Y71H2AM.13
    Corresponding_transcript: Y71H2AM.13.1
    Other_sequence: CJC02932_1
      Acan_isotig14319
      CR07251
      AS15591
      FE916521.1
      CJC02777_1
      CRC07493_1
    Associated_feature: WBsf650885
      WBsf991592
      WBsf991593
      WBsf1014450
      WBsf1014451
      WBsf226299
  Experimental_info: RNAi_result: WBRNAi00000855 Inferred_automatically: RNAi_primary
      WBRNAi00058235 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1021215
      Expr1039778
      Expr1161654
      Expr2008318
      Expr2026558
    Microarray_results (19)
    Expression_cluster (178)
    Interaction: WBInteraction000253182
      WBInteraction000253220
      WBInteraction000362645
      WBInteraction000464617
      WBInteraction000585078
  Map_info: Positive: Positive_clone: Y71H2AM Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: III -10.7432
  Method: Gene