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WormBase Tree Display for Gene: WBGene00022178

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Name Class

WBGene00022178SMapS_parentSequenceY71H2AM
IdentityVersion2
NameCGC_namecest-25Person_evidenceWBPerson36909
WBPerson7188
Sequence_nameY71H2AM.13
Molecular_nameY71H2AM.13
Y71H2AM.13.1
CE22953
Other_nameCELE_Y71H2AM.13Accession_evidenceNDBBX284603
Public_namecest-25
DB_infoDatabaseAceViewgene3D824
WormQTLgeneWBGene00022178
WormFluxgeneWBGene00022178
NDBlocus_tagCELE_Y71H2AM.13
PanthergeneCAEEL|WormBase=WBGene00022178|UniProtKB=Q9BL43
familyPTHR44590
NCBIgene175390
RefSeqproteinNM_065208.8
TrEMBLUniProtAccQ9BL43
UniProt_GCRPUniProtAccQ9BL43
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:05WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
220 May 2019 14:10:26WBPerson1983Name_changeCGC_namecest-25
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcest
Allele (132)
RNASeq_FPKM (74)
Ortholog (34)
Paralog (41)
Structured_descriptionAutomated_descriptionEnriched in several structures, including dopaminergic neurons; excretory cell; mc2; mechanosensory neurons; and somatic gonad precursor based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by eleven chemicals including D-glucose; Sodium Chloride; and Rifampin based on RNA-seq; microarray; and proteomic studies. Human ortholog(s) of this gene implicated in colorectal cancer; hepatocellular carcinoma; and stomach cancer. Human CES1 enables carboxylesterase activity and sterol esterase activity. Is predicted to encode a protein with the following domains: Alpha/Beta hydrolase fold; Carboxylesterase, type B; and Carboxylesterase family. Is an ortholog of human CES1 (carboxylesterase 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:9256Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:1863)
DOID:3119Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:1863)
DOID:10534Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:1863)
DOID:684Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:1863)
Molecular_infoCorresponding_CDSY71H2AM.13
Corresponding_transcriptY71H2AM.13.1
Other_sequenceCJC02932_1
Acan_isotig14319
CR07251
AS15591
FE916521.1
CJC02777_1
CRC07493_1
Associated_featureWBsf650885
WBsf991592
WBsf991593
WBsf1014450
WBsf1014451
WBsf226299
Experimental_infoRNAi_resultWBRNAi00000855Inferred_automaticallyRNAi_primary
WBRNAi00058235Inferred_automaticallyRNAi_primary
Expr_patternExpr1021215
Expr1039778
Expr1161654
Expr2008318
Expr2026558
Microarray_results (19)
Expression_cluster (178)
InteractionWBInteraction000253182
WBInteraction000253220
WBInteraction000362645
WBInteraction000464617
WBInteraction000585078
Map_infoPositivePositive_cloneY71H2AMInferred_automaticallyFrom sequence, transcript, pseudogene data
Interpolated_map_positionIII-10.7432
MethodGene