Questions, Feedback & Help
Send us an email and we'll get back to you ASAP. Or you can read our Frequently Asked Questions.

WormBase Tree Display for Gene: WBGene00021784

expand all nodes | collapse all nodes | view schema

Name Class

WBGene00021784SMapS_parentSequenceY51H7C
IdentityVersion3
NameCGC_namecogc-4Paper_evidenceWBPaper00026979
Person_evidenceWBPerson449
Sequence_nameY51H7C.6
Molecular_nameY51H7C.6a
Y51H7C.6a.1
CE26151
Y51H7C.6b
CE26152
Y51H7C.6c
CE39055
Y51H7C.6b.1
Y51H7C.6c.1
Other_nameY51H7C.kCurator_confirmedWBPerson1983
RemarkOld cosmid naming mapped via unique overlapping PCR_product on CDSs
Y51H7C.oCurator_confirmedWBPerson1983
RemarkOld cosmid naming mapped via unique overlapping PCR_product on CDSs
CELE_Y51H7C.6Accession_evidenceNDBBX284602
Public_namecogc-4
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:05WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
216 Jan 2006 17:07:41WBPerson2970Name_changeCGC_namecogc-4
306 Mar 2018 14:49:17WBPerson4025EventSplit_intoWBGene00302984
Split_intoWBGene00302984
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcogc
Allele (106)
Possibly_affected_byWBVar02153274
RNASeq_FPKM (74)
GO_annotation00089442
00089443
00089444
00089445
00089446
00089447
00089448
00089449
00089450
00089451
Contained_in_operonCEOP2048
CEOP5602
Ortholog (41)
Structured_descriptionConcise_descriptioncogc-4 encodes an ortholog of mammalian COG-4, a subunit of lobe A ofthe conserved oligomeric Golgi complex (COGC); COGC-4 is required fornormal gonadal distal tip cell migration, a process that also requiresseven other orthologs of COGC subunits; like other lobe A subunits inboth C. elegans and S. cerevisiae, COGC-4 is strongly required fornormal function, while lobe B subunits are only partially required ineither worms or yeast.Paper_evidenceWBPaper00026979
WBPaper00028363
WBPaper00028599
WBPaper00028603
Curator_confirmedWBPerson567
Date_last_updated25 Oct 2006 00:00:00
Automated_descriptionInvolved in gonad morphogenesis and regulation of cell migration. Predicted to be located in Golgi membrane. Predicted to be part of Golgi transport complex. Human ortholog(s) of this gene implicated in Saul-Wilson syndrome and congenital disorder of glycosylation type IIj. Is an ortholog of human COG4 (component of oligomeric golgi complex 4).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0070262Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:18620)
DOID:0111673Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:18620)
Molecular_infoCorresponding_CDSY51H7C.6a
Y51H7C.6b
Y51H7C.6c
Corresponding_CDS_historyY51H7C.6d:wp264
Corresponding_transcriptY51H7C.6a.1
Y51H7C.6b.1
Y51H7C.6c.1
Other_sequence (21)
Associated_featureWBsf643960
WBsf657339
WBsf657340
WBsf986677
WBsf986678
WBsf1011545
WBsf1011546
WBsf220841
WBsf220842
WBsf220843
Experimental_infoRNAi_result (24)
Expr_patternExpr1019942
Expr1039553
Expr1160649
Expr2010293
Expr2028535
Microarray_results (45)
Expression_cluster (83)
SAGE_tagSAGE:ttctttgaagStrandSense
Unambiguously_mapped
SAGE:ctcgtcgtcgStrandSense
Unambiguously_mapped
SAGE:aacccgacgagggattaStrandSense
Unambiguously_mapped
SAGE:aacaaagtgtcagcgtaStrandAntisense
SAGE:aagaattcgacacccgaStrandSense
Unambiguously_mapped
SAGE:aagaattcgaStrandSense
Unambiguously_mapped
Interaction (30)
Map_infoMapIIPosition-15.456Error0.003345
PositivePositive_cloneY51H7CInferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00038491
WBPaper00055090
WBPaper00061076
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene