WormBase Tree Display for Gene: WBGene00021470
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| WBGene00021470 | SMap | S_parent | Sequence | Y39G10AR | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | tpxl-1 | Person_evidence | WBPerson1480 | |||||
| Sequence_name | Y39G10AR.12 | ||||||||
| Molecular_name | Y39G10AR.12a | ||||||||
| Y39G10AR.12a.1 | |||||||||
| CE26990 | |||||||||
| Y39G10AR.12b | |||||||||
| CE29999 | |||||||||
| Y39G10AR.12b.1 | |||||||||
| Other_name | CELE_Y39G10AR.12 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | tpxl-1 | ||||||||
| DB_info | Database | AceView | gene | 1C866 | |||||
| WormQTL | gene | WBGene00021470 | |||||||
| WormFlux | gene | WBGene00021470 | |||||||
| NDB | locus_tag | CELE_Y39G10AR.12 | |||||||
| NCBI | gene | 171786 | |||||||
| RefSeq | protein | NM_170822.8 | |||||||
| NM_170821.7 | |||||||||
| TREEFAM | TREEFAM_ID | TF317968 | |||||||
| TrEMBL | UniProtAcc | G5EDE7 | |||||||
| Q8WSN6 | |||||||||
| UniProt_GCRP | UniProtAcc | G5EDE7 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:04 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 09 Jun 2005 10:01:00 | WBPerson2970 | Name_change | CGC_name | tpxl-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | tpxl | ||||||||
| Allele (152) | |||||||||
| Strain | WBStrain00034715 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (12) | |||||||||
| Contained_in_operon | CEOP1910 | ||||||||
| Ortholog (21) | |||||||||
| Structured_description | Concise_description | tpxl-1 encodes the C. elegans ortholog of Xenopus laevis TPX2; during mitosis, TPXL-1 activity is required for activation and localization of the AIR-1 Aurora A kinase to mitotic spindles, and thus for proper mitotic spindle assembly; like TPX2, TPXL-1 physically interacts with the Aurora A kinase AIR-1 in vitro, and colocalizes with AIR-1 at the centrosome, particularly the outer centrosomal layer, and along microtubules extended outward from the centrosome. | Paper_evidence | WBPaper00026659 | |||||
| WBPaper00028993 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 11 Feb 2010 00:00:00 | ||||||||
| Automated_description | Enables protein kinase binding activity. Involved in astral microtubule organization and mitotic spindle assembly. Located in astral microtubule; meiotic spindle; and spindle pole centrosome. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | Y39G10AR.12a | |||||||
| Y39G10AR.12b | |||||||||
| Corresponding_transcript | Y39G10AR.12a.1 | ||||||||
| Y39G10AR.12b.1 | |||||||||
| Other_sequence | CBC08748_1 | ||||||||
| BMC18450_1 | |||||||||
| CR01972 | |||||||||
| JI461455.1 | |||||||||
| CRC06364_1 | |||||||||
| BM01571 | |||||||||
| Associated_feature (13) | |||||||||
| Experimental_info | RNAi_result (23) | ||||||||
| Expr_pattern | Expr3653 | ||||||||
| Expr1012859 | |||||||||
| Expr1039383 | |||||||||
| Expr1159747 | |||||||||
| Expr2017474 | |||||||||
| Expr2035613 | |||||||||
| Drives_construct | WBCnstr00000354 | ||||||||
| Antibody | WBAntibody00000869 | ||||||||
| WBAntibody00000870 | |||||||||
| Microarray_results (30) | |||||||||
| Expression_cluster (202) | |||||||||
| Interaction (39) | |||||||||
| Map_info | Map | I | Position | -9.71714 | Error | 0.072119 | |||
| Positive | Positive_clone | Y39G10AR | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (18) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
