WormBase Tree Display for Gene: WBGene00021331

WBGene00021331 SMap: S_parent: Sequence: Y34D9A
  Identity: Version: 2
    Name: CGC_name: glrx-10 Person_evidence: WBPerson83
      Sequence_name: Y34D9A.6
      Molecular_name: Y34D9A.6
        Y34D9A.6.1
        CE25238
      Other_name: Y34D9A.k Curator_confirmed: WBPerson1983
          Remark: Old cosmid naming mapped via unique overlapping PCR_product on CDSs
        CELE_Y34D9A.6 Accession_evidence: NDB BX284601
      Public_name: glrx-10
    DB_info: Database: AceView gene 1B523
        WormQTL gene WBGene00021331
        WormFlux gene WBGene00021331
        NDB locus_tag CELE_Y34D9A.6
        Panther gene CAEEL|WormBase=WBGene00021331|UniProtKB=Q9N456
          family PTHR46185
        NCBI gene 171685
        RefSeq protein NM_058411.6
        TREEFAM TREEFAM_ID TF326994
        TrEMBL UniProtAcc Q9N456
        UniProt_GCRP UniProtAcc Q9N456
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:04 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 19 May 2006 11:42:44 WBPerson2970 Name_change: CGC_name: glrx-10
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: glrx
    Allele (49)
    Strain: WBStrain00001997
    RNASeq_FPKM (74)
    GO_annotation: 00094235
    Contained_in_operon: CEOP1908
    Ortholog (38)
    Structured_description: Concise_description: glrx-10 encodes a glutaredoxin, oxidoreductases of the thioredoxin family; by homology, GLRX-10 is predicted to function in regulation of the thiol redox state of proteins. Paper_evidence: WBPaper00036400
            WBPaper00040582
          Curator_confirmed: WBPerson1843
          Date_last_updated: 28 May 2014 00:00:00
      Automated_description: Predicted to enable glutathione disulfide oxidoreductase activity. Used to study Parkinson's disease. Is an ortholog of human GLRX (glutaredoxin). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Experimental_model: DOID:14330 Homo sapiens Paper_evidence: WBPaper00045963
          Curator_confirmed: WBPerson324
          Date_last_updated: 04 Feb 2015 00:00:00
    Disease_relevance: Parkinson''s disease (PD) is characterized by the selective degeneration of dopaminergic neurons Homo sapiens Curator_confirmed: WBPerson324
  Models_disease_in_annotation: WBDOannot00000343
  Molecular_info: Corresponding_CDS: Y34D9A.6
    Corresponding_transcript: Y34D9A.6.1
    Other_sequence (54)
    Associated_feature: WBsf643038
      WBsf654768
      WBsf980935
      WBsf982652
      WBsf1009182
      WBsf217179
  Experimental_info: RNAi_result: WBRNAi00117099 Inferred_automatically: RNAi_primary
      WBRNAi00115569 Inferred_automatically: RNAi_primary
      WBRNAi00115508 Inferred_automatically: RNAi_primary
      WBRNAi00036770 Inferred_automatically: RNAi_primary
      WBRNAi00004574 Inferred_automatically: RNAi_primary
      WBRNAi00055832 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr6928
      Expr1011775
      Expr1039305
      Expr1159360
      Expr2012120
      Expr2030356
    Drives_construct: WBCnstr00002781
    Microarray_results (18)
    Expression_cluster (114)
    Interaction (88)
  Map_info: Map: I Position: -17.2445 Error: 0.065927
    Positive: Positive_clone: Y34D9A Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00035500
    WBPaper00038491
    WBPaper00041408
    WBPaper00045963
    WBPaper00055090
    WBPaper00061547
    WBPaper00064339
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene