WormBase Tree Display for Gene: WBGene00021074

WBGene00021074 SMap: S_parent: Sequence: W07E6
  Identity: Version: 2
    Name: CGC_name: gldi-1 Person_evidence: WBPerson6609
            WBPerson1816
      Sequence_name: W07E6.2
      Molecular_name: W07E6.2a
        W07E6.2a.1
        CE17294
        W07E6.2b
        CE51055
        W07E6.2b.1
      Other_name: CELE_W07E6.2 Accession_evidence: NDB BX284602
      Public_name: gldi-1
    DB_info: Database: AceView gene 2A772
        WormQTL gene WBGene00021074
        SignaLink protein WBGene00021074
        WormFlux gene WBGene00021074
        NDB locus_tag CELE_W07E6.2
        Panther gene CAEEL|WormBase=WBGene00021074|UniProtKB=Q9TYV3
          family PTHR19848
        NCBI gene 173439
        RefSeq protein NM_001316868.3
            NM_061344.5
        TrEMBL UniProtAcc Q9TYV3
            A0A0M9JJ65
        UniProt_GCRP UniProtAcc Q9TYV3
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:04 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 05 May 2023 12:43:53 WBPerson51134 Name_change: CGC_name: gldi-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: gldi
    Allele (59)
    RNASeq_FPKM (74)
    GO_annotation: 00001779
      00001780
      00097677
      00097678
      00097679
    Ortholog (38)
    Structured_description: Concise_description: W07E6.2 encodes an ortholog of S. cerevisiae RSA4 that may suppress tumorous growth in the germ line by ensuring robust larval germline proliferation; like PRO-1, -2, and -3, W07E6.2 is probably required for ribosome biogenesis, suggesting a link between biogenesis in the distal sheath and control of cell division in the germ line. Paper_evidence: WBPaper00028280
            WBPaper00028933
          Curator_confirmed: WBPerson567
          Date_last_updated: 23 Apr 2008 00:00:00
      Automated_description: Predicted to be involved in Notch signaling pathway. Predicted to be located in nucleolus. Is an ortholog of human NLE1 (notchless homolog 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: W07E6.2a
      W07E6.2b
    Corresponding_transcript: W07E6.2a.1
      W07E6.2b.1
    Other_sequence (55)
    Associated_feature: WBsf649825
      WBsf665327
      WBsf665328
      WBsf986418
      WBsf1011400
      WBsf222609
      WBsf222610
  Experimental_info: RNAi_result (15)
    Expr_pattern: Expr1021160
      Expr1039193
      Expr1158484
      Expr2006840
      Expr2025065
    Microarray_results (18)
    Expression_cluster: WBPaper00033065:cyc-1(RNAi)_upregulated
      WBPaper00037950:bodywall-muscle_L2-larva_expressed
      WBPaper00037950:bodywall-muscle_larva_enriched
      WBPaper00037950:CEP-sheath-cells_Day1-adult_expressed
      WBPaper00037950:coelomocytes_L2-larva_expressed
      WBPaper00037950:dopaminergic-neurons_L3-L4-larva_expressed
      WBPaper00037950:excretory-cell_L2-larva_expressed
      WBPaper00037950:GABAergic-motor-neurons_L2-larva_expressed
      WBPaper00037950:glr-1(+)-neurons_L2-larva_expressed
      WBPaper00037950:hypodermis_L3-L4-larva_expressed
      WBPaper00037950:intestine_L1-larva_expressed
      WBPaper00037950:intestine_L2-larva_expressed
      WBPaper00037950:pharyngeal-muscle_L1-larva_expressed
      WBPaper00037950:PVD-OLL-neurons_L3-L4-larva_expressed
      WBPaper00040560:hpl-2_embryo_downregulated
      WBPaper00042477:prp-8(RNAi)_upregulated_RNAseq
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_upregulated_12h
      WBPaper00047132:skn-1(RNAi)_downregulated_glp-1(ts)-dependent
      WBPaper00048923:Aging_regulated
      WBPaper00048988:neuron_expressed
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00050080:rbr-2(tm3141)_downregulated
      WBPaper00050234:lin-28(RNAi)_upregulated
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050686:glp-1(e2141)_downregulated
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050801:DAF-16_dauer_regulome
      WBPaper00050801:DPY-21_dauer_regulome
      WBPaper00050990:GABAergic-neuron_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:body-wall-muscle_nucleus_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:nucleus_specific
      WBPaper00051558:aging_regulated
      WBPaper00052884:emb-4(hc60)_upregulated
      WBPaper00053184:sma-4(rax3)_upregulated
      WBPaper00053295:lin-22(ot269)_upregulated
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00053599:oocyte_vs_mitosis_upregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00055354:Allantoin_upregulated
      WBPaper00055354:eat-2(ad1116)_downregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056826:SGP_biased
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058598:sin-3(tm1276)_downregulated
      WBPaper00058691:cfp-1(tm6369)_downregulated
      WBPaper00058691:sin-3(tm1276)_downregulated
      WBPaper00058725:sftb-1(cer6)_upregulated
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061203:sin-3(tm1276)_upregulated
      WBPaper00061340:M_cell
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061527:trm-1-H43I07.2
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:etr-1(lq61)_downregulated
      WBPaper00062520:qui-1(db104)_downregulated
      WBPaper00062590:Aging_upregulated_body-wall-muscle
      WBPaper00062590:Aging_upregulated_intestine
      WBPaper00062590:Aging_upregulated_neuron
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064005:starvation_upregulated_aptf-1(gk794)_mRNA
      WBPaper00064005:starvation_upregulated_N2_mRNA
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_fem-3(q20)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00065258:anchor-cell_depleted
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065841:1_0
      WBPaper00065841:11_0
      WBPaper00065945:epidermis-rpoa-2(-)_upregulated_protein
      WBPaper00065945:global-rpoa-2(-)_upregulated_transcript
      WBPaper00065993:glp-1(e2141)_downregulated
      cgc4489_group_3
      WBPaper00024393:strongly_regulated_dauer_genes
      WBPaper00025032:cluster_7
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00032062:age_regulated_genes
      WBPaper00032165:differentially_expressed_with_age_medoid_7
      WBPaper00035905:FBF-1_Associated
      WBPaper00036123:Cadmium_regulated
      WBPaper00036286:Pattern_E
      WBPaper00037695:WC_5-day
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00041939:control_vs_UVC-EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_EtBr-exposed_51h
      WBPaper00041939:UVC-EtBr-exposed_vs_UVC-exposed_51h
      WBPaper00041960:N2_fasting_upregulated_anytime
      WBPaper00045263:isp-1(qm150)_downregulated
      WBPaper00045263:nuo-6(qm200)_downregulated
      WBPaper00047070:DAF-16-dependent_UV_response
      WBPaper00047070:N2_UV_upregulated
      WBPaper00048989:eat-2(ad465)_rapamycin_downregulated
      WBPaper00048989:N2_rapamycin_upregulated
      WBPaper00053236:Starvation_regulated_N2
      [cgc5767]:cluster_2
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(66_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
      [cgc6390]:intrinsic
    Interaction (147)
  Map_info: Map: II Position: -15.6026
    Positive: Positive_clone: W07E6 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00028280
    WBPaper00038491
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene