WormBase Tree Display for Gene: WBGene00021070

WBGene00021070 SMap: S_parent: Sequence: W07B8
  Identity: Version: 2
    Name: CGC_name: cpr-8
      Sequence_name: W07B8.1
      Molecular_name: W07B8.1a
        W07B8.1a.1
        CE14674
        W07B8.1b
      Other_name: drd-3 Paper_evidence: WBPaper00044557
          Person_evidence: WBPerson10050
        CELE_W07B8.1 Accession_evidence: NDB BX284605
      Public_name: cpr-8
    DB_info: Database: AceView gene 5B617
        WormQTL gene WBGene00021070
        WormFlux gene WBGene00021070
        NDB locus_tag CELE_W07B8.1
        Panther gene CAEEL|WormBase=WBGene00021070|UniProtKB=O16289
          family PTHR12411
        NCBI gene 178613
        RefSeq protein NM_070983.7
            NR_132498.1
        TrEMBL UniProtAcc O16289
        UniProt_GCRP UniProtAcc O16289
        RNAcentral URSid URS0000843C85
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:04 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 29 Apr 2015 12:07:40 WBPerson2970 Name_change: CGC_name: cpr-8
                Other_name: drd-3
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: cpr
    Allele (84)
    Strain: WBStrain00032862
    RNASeq_FPKM (74)
    GO_annotation: 00027684
      00027685
      00027686
      00125538
      00125539
    Ortholog (39)
    Paralog (28)
    Structured_description: Automated_description: Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease of the nervous system (multiple); carcinoma (multiple); and type 2 diabetes mellitus. Is an ortholog of human CTSB (cathepsin B). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:9351 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:11054 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:2671 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:9352 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:2377 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:10941 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:12842 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:3068 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:4914 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
      DOID:1612 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2527)
  Molecular_info: Corresponding_CDS: W07B8.1a
    Corresponding_transcript: W07B8.1b
      W07B8.1a.1
    Associated_feature: WBsf999258
      WBsf999259
      WBsf1019135
      WBsf1019136
      WBsf231385
  Experimental_info: RNAi_result: WBRNAi00115176 Inferred_automatically: RNAi_primary
      WBRNAi00089178 Inferred_automatically: RNAi_primary
      WBRNAi00076746 Inferred_automatically: RNAi_primary
      WBRNAi00019692 Inferred_automatically: RNAi_primary
      WBRNAi00036358 Inferred_automatically: RNAi_primary
      WBRNAi00054940 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr1014103
      Expr1158475
      Expr2010508
      Expr2028748
    Microarray_results (19)
    Expression_cluster (221)
    Interaction: WBInteraction000108869
      WBInteraction000227593
      WBInteraction000292392
      WBInteraction000382485
      WBInteraction000455274
      WBInteraction000459558
      WBInteraction000503272
  Map_info: Map: V Position: -19.8519
    Positive: Positive_clone: W07B8 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00044557
    WBPaper00055090
    WBPaper00059755
    WBPaper00061178
    WBPaper00064130
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene