WormBase Tree Display for Gene: WBGene00021063
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| WBGene00021063 | SMap | S_parent | Sequence | W06E11 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | sbds-1 | Person_evidence | WBPerson8131 | |||||
| Sequence_name | W06E11.4 | ||||||||
| Molecular_name | W06E11.4 | ||||||||
| W06E11.4.1 | |||||||||
| CE30118 | |||||||||
| Other_name | W06E11.c | Curator_confirmed | WBPerson1983 | ||||||
| Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
| CELE_W06E11.4 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | sbds-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:04 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 04 Jun 2008 11:48:40 | WBPerson2970 | Name_change | CGC_name | sbds-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | sbds | ||||||||
| Allele (41) | |||||||||
| Strain | WBStrain00051204 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00077608 | ||||||||
| 00077609 | |||||||||
| 00077610 | |||||||||
| 00077611 | |||||||||
| 00077612 | |||||||||
| 00077613 | |||||||||
| 00077614 | |||||||||
| 00077615 | |||||||||
| 00125534 | |||||||||
| 00125535 | |||||||||
| Contained_in_operon | CEOP3028 | ||||||||
| Ortholog (36) | |||||||||
| Structured_description | Concise_description | W06E11.4 encodes an ortholog of human SBDS (OMIM:607444, mutated in Shwachman-Bodian-Diamond syndrome) and S. cerevisiae Sdo1p, that is required for the extended lifespan of daf-2(e1370) mutants; W06E11.4 is expressed ubiquitously (or nearly so) in somatic larval and adult tissues; by orthology with yeast Sdo1p, W06E11.4 is predicted to be a nucleolar protein required for maturation of 60S ribosomal subunits; W06E11.4 shares an operon with tag-266 and T19C3.7. | Paper_evidence | WBPaper00028829 | |||||
| WBPaper00028832 | |||||||||
| WBPaper00028833 | |||||||||
| WBPaper00028836 | |||||||||
| WBPaper00031212 | |||||||||
| WBPaper00032020 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 24 Jul 2008 00:00:00 | ||||||||
| Automated_description | Predicted to be involved in cytosolic ribosome assembly. Predicted to be located in cytoplasm; nuclear lumen; and spindle. Human ortholog(s) of this gene implicated in Shwachman-Diamond syndrome and aplastic anemia. Is an ortholog of human SBDS (SBDS ribosome maturation factor). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:12449 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:19440) | ||||
| DOID:0060479 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:19440) | ||||||
| Molecular_info | Corresponding_CDS | W06E11.4 | |||||||
| Corresponding_transcript | W06E11.4.1 | ||||||||
| Other_sequence (91) | |||||||||
| Associated_feature | WBsf226118 | ||||||||
| WBsf226119 | |||||||||
| Experimental_info | RNAi_result (12) | ||||||||
| Expr_pattern | Expr1013363 | ||||||||
| Expr1039189 | |||||||||
| Expr1158436 | |||||||||
| Expr2015610 | |||||||||
| Expr2033845 | |||||||||
| Drives_construct | WBCnstr00024700 | ||||||||
| Construct_product | WBCnstr00024700 | ||||||||
| Microarray_results (19) | |||||||||
| Expression_cluster (115) | |||||||||
| Interaction (47) | |||||||||
| Map_info | Map | III | Position | -26.4304 | Error | 0.009723 | |||
| Positive | Positive_clone | W06E11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00030887 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
