WormBase Tree Display for Gene: WBGene00021063
expand all nodes | collapse all nodes | view schema
WBGene00021063 | SMap | S_parent | Sequence | W06E11 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | sbds | ||||||
Allele (41) | |||||||
Strain | WBStrain00051204 | ||||||
RNASeq_FPKM (74) | |||||||
GO_annotation | 00077608 | ||||||
00077609 | |||||||
00077610 | |||||||
00077611 | |||||||
00077612 | |||||||
00077613 | |||||||
00077614 | |||||||
00077615 | |||||||
00125534 | |||||||
00125535 | |||||||
Contained_in_operon | CEOP3028 | ||||||
Ortholog (36) | |||||||
Structured_description | Concise_description | W06E11.4 encodes an ortholog of human SBDS (OMIM:607444, mutated in Shwachman-Bodian-Diamond syndrome) and S. cerevisiae Sdo1p, that is required for the extended lifespan of daf-2(e1370) mutants; W06E11.4 is expressed ubiquitously (or nearly so) in somatic larval and adult tissues; by orthology with yeast Sdo1p, W06E11.4 is predicted to be a nucleolar protein required for maturation of 60S ribosomal subunits; W06E11.4 shares an operon with tag-266 and T19C3.7. | Paper_evidence | WBPaper00028829 | |||
WBPaper00028832 | |||||||
WBPaper00028833 | |||||||
WBPaper00028836 | |||||||
WBPaper00031212 | |||||||
WBPaper00032020 | |||||||
Curator_confirmed | WBPerson567 | ||||||
Date_last_updated | 24 Jul 2008 00:00:00 | ||||||
Automated_description | Predicted to be involved in cytosolic ribosome assembly. Predicted to be located in cytoplasm; nuclear lumen; and spindle. Human ortholog(s) of this gene implicated in Shwachman-Diamond syndrome and aplastic anemia. Is an ortholog of human SBDS (SBDS ribosome maturation factor). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:12449 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:19440) | ||
DOID:0060479 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:19440) | ||||
Molecular_info | Corresponding_CDS | W06E11.4 | |||||
Corresponding_transcript | W06E11.4.1 | ||||||
Other_sequence (91) | |||||||
Associated_feature | WBsf226118 | ||||||
WBsf226119 | |||||||
Experimental_info | RNAi_result (12) | ||||||
Expr_pattern | Expr1013363 | ||||||
Expr1039189 | |||||||
Expr1158436 | |||||||
Expr2015610 | |||||||
Expr2033845 | |||||||
Drives_construct | WBCnstr00024700 | ||||||
Construct_product | WBCnstr00024700 | ||||||
Microarray_results (19) | |||||||
Expression_cluster (115) | |||||||
Interaction (47) | |||||||
Map_info | Map | III | Position | -26.4304 | Error | 0.009723 | |
Positive | Positive_clone | W06E11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference | WBPaper00030887 | ||||||
WBPaper00038491 | |||||||
WBPaper00055090 | |||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |