WormBase Tree Display for Gene: WBGene00020509
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| WBGene00020509 | SMap | S_parent | Sequence | T14F9 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | hex-1 | Person_evidence | WBPerson2099 | |||||
| Sequence_name | T14F9.3 | ||||||||
| Molecular_name | T14F9.3 | ||||||||
| T14F9.3.1 | |||||||||
| CE07499 | |||||||||
| T14F9.3.2 | |||||||||
| Other_name | CELE_T14F9.3 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | hex-1 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:03 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 19 Jul 2007 09:29:24 | WBPerson2970 | Name_change | CGC_name | hex-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | hex | ||||||||
| Allele (68) | |||||||||
| Strain | WBStrain00002884 | ||||||||
| In_cluster | conserved_RDE-1_cluster | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (21) | |||||||||
| Ortholog (41) | |||||||||
| Structured_description | Concise_description | hex-1 encodes a beta-N-acetylhexosaminidase that is orthologous to the human gene CERVICAL CANCER PROTO-ONCOGENE 7 (HEXB; OMIM:606873), which when mutated leads to disease. | Paper_evidence | WBPaper00030867 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson1823 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 23 Jul 2007 00:00:00 | ||||||||
| Automated_description | Enables beta-N-acetylhexosaminidase activity. Involved in carbohydrate metabolic process. Predicted to be located in lysosome and membrane. Expressed in coelomocyte and pharyngeal neurons. Human ortholog(s) of this gene implicated in Sandhoff disease; Tay-Sachs disease; and spinal muscular atrophy. Is an ortholog of human HEXA (hexosaminidase subunit alpha) and HEXB (hexosaminidase subunit beta). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:12377 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4879) | ||||
| DOID:3323 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4879) | ||||||
| DOID:3320 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4878) | ||||||
| Molecular_info | Corresponding_CDS | T14F9.3 | |||||||
| Corresponding_transcript | T14F9.3.1 | ||||||||
| T14F9.3.2 | |||||||||
| Other_sequence (41) | |||||||||
| Associated_feature | WBsf655166 | ||||||||
| WBsf662510 | |||||||||
| WBsf662511 | |||||||||
| WBsf1004268 | |||||||||
| WBsf235376 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00053327 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00018714 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00035568 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Chronogram1816 | ||||||||
| Expr4821 | |||||||||
| Expr6695 | |||||||||
| Expr1019152 | |||||||||
| Expr1038942 | |||||||||
| Expr1156913 | |||||||||
| Expr2012401 | |||||||||
| Expr2030637 | |||||||||
| Drives_construct | WBCnstr00003403 | ||||||||
| WBCnstr00004955 | |||||||||
| WBCnstr00025086 | |||||||||
| Construct_product | WBCnstr00025086 | ||||||||
| Microarray_results (22) | |||||||||
| Expression_cluster (276) | |||||||||
| Interaction (124) | |||||||||
| Map_info | Map | X | Position | -16.3239 | Error | 0.135409 | |||
| Positive | Positive_clone | T14F9 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00030867 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00059755 | |||||||||
| WBPaper00062715 | |||||||||
| WBPaper00065036 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
