WormBase Tree Display for Gene: WBGene00020392
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| WBGene00020392 | SMap | S_parent | Sequence | T10B5 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | knl-3 | Person_evidence | WBPerson283 | |||||
| Sequence_name | T10B5.6 | ||||||||
| Molecular_name | T10B5.6 | ||||||||
| T10B5.6.1 | |||||||||
| CE18236 | |||||||||
| Other_name | CELE_T10B5.6 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | knl-3 | ||||||||
| DB_info | Database | AceView | gene | 5C349 | |||||
| WormQTL | gene | WBGene00020392 | |||||||
| WormFlux | gene | WBGene00020392 | |||||||
| NDB | locus_tag | CELE_T10B5.6 | |||||||
| NCBI | gene | 178669 | |||||||
| RefSeq | protein | NM_071119.9 | |||||||
| TREEFAM | TREEFAM_ID | TF318547 | |||||||
| TrEMBL | UniProtAcc | O76406 | |||||||
| UniProt_GCRP | UniProtAcc | O76406 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:03 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 05 Jul 2004 16:31:00 | WBPerson1971 | Name_change | CGC_name | knl-3 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | knl | ||||||||
| Allele (31) | |||||||||
| Strain | WBStrain00037086 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00038350 | ||||||||
| 00038351 | |||||||||
| 00038352 | |||||||||
| 00038353 | |||||||||
| 00038354 | |||||||||
| 00038355 | |||||||||
| 00038356 | |||||||||
| 00038357 | |||||||||
| 00038358 | |||||||||
| 00038359 | |||||||||
| Contained_in_operon | CEOP5560 | ||||||||
| Ortholog (21) | |||||||||
| Structured_description | Concise_description | knl-3 encodes a novel protein; KNL-3 activity is essential for formation of a functional kinetochore and thus, for proper chromosome segregation and spindle pole separation; KNL-3 localizes to kinetochores throughout mitosis and this localization requires the activity of HCP-4 (CENP-C), a conserved kinetochore component that likely directs kinetochore assembly; KNL-3 copurifies with a group of 10 closely interacting kinetochore proteins that includes KNL-1, NDC-80, MIS-12, HIM-10, and KBP-1, -2, -3, -4, and-5; KNL-3 also copurifies with HCP-4(CENP-C). | Paper_evidence | WBPaper00024437 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 28 Jun 2006 00:00:00 | ||||||||
| Automated_description | Involved in several processes, including chromosome organization; positive regulation of cell cycle process; and positive regulation of kinetochore assembly. Located in kinetochore. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | T10B5.6 | |||||||
| Corresponding_transcript | T10B5.6.1 | ||||||||
| Other_sequence | CJC00365_1 | ||||||||
| CRC08427_1 | |||||||||
| CBC09796_1 | |||||||||
| CR01984 | |||||||||
| Associated_feature | WBsf646684 | ||||||||
| WBsf981897 | |||||||||
| WBsf231444 | |||||||||
| WBsf231445 | |||||||||
| WBsf231446 | |||||||||
| Experimental_info | RNAi_result (21) | ||||||||
| Expr_pattern | Expr3438 | ||||||||
| Expr3671 | |||||||||
| Expr1027704 | |||||||||
| Expr1038889 | |||||||||
| Expr1156610 | |||||||||
| Expr2012974 | |||||||||
| Expr2031206 | |||||||||
| Construct_product | WBCnstr00000891 | ||||||||
| WBCnstr00005324 | |||||||||
| WBCnstr00011589 | |||||||||
| Antibody | WBAntibody00000764 | ||||||||
| WBAntibody00001002 | |||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (163) | |||||||||
| Interaction (106) | |||||||||
| Map_info | Map | V | Position | -16.944 | Error | 0.029379 | |||
| Positive | Positive_clone | T10B5 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (15) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
