WormBase Tree Display for Gene: WBGene00020292

WBGene00020292 SMap: S_parent: Sequence: T06D4
  Identity: Version: 3
    Name: CGC_name: nep-19 Person_evidence: WBPerson260
      Sequence_name: T06D4.3
      Molecular_name: T06D4.3
      Other_name: CELE_T06D4.3 Accession_evidence: NDB BX284602
      Public_name: nep-19
    DB_info: Database: AceView gene 2D678
        WormQTL gene WBGene00020292
        WormFlux gene WBGene00020292
        NDB locus_tag CELE_T06D4.3
        NCBI gene 188175
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:02 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 10 Feb 2012 15:49:10 WBPerson2970 Name_change: CGC_name: nep-19
        3 21 Nov 2019 15:08:29 WBPerson4025 Event: Changed_class: CDS Pseudogene
    Status: Live
  Gene_info: Biotype: SO:0000336
    Gene_class: nep
    Allele (169)
    RNASeq_FPKM (74)
    Ortholog: WBGene00072706 Caenorhabditis remanei From_analysis: OMA
      WBGene00140052 Caenorhabditis brenneri From_analysis: OMA
      WBGene00067448 Caenorhabditis remanei From_analysis: OMA
            TreeFam
      WBGene00037321 Caenorhabditis briggsae From_analysis: OMA
      WBGene00152932 Caenorhabditis brenneri From_analysis: OMA
      WBGene00124951 Caenorhabditis japonica From_analysis: Inparanoid_8
      WBGene00120176 Caenorhabditis japonica From_analysis: Inparanoid_8
      WBGene00132014 Caenorhabditis japonica From_analysis: Inparanoid_8
      WBGene00127165 Caenorhabditis japonica From_analysis: Inparanoid_8
      WBGene00127171 Caenorhabditis japonica From_analysis: Inparanoid_8
    Paralog (20)
    Structured_description: Concise_description: T06D4.3 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; T06D4.3 has no clear orthologs in other organisms. Paper_evidence: WBPaper00004584
            WBPaper00013276
          Curator_confirmed: WBPerson567
          Date_last_updated: 17 Jun 2004 00:00:00
      Automated_description: Enriched in male based on RNA-seq studies. Is affected by several genes including skn-1; eat-2; and sir-2.1 based on tiling array; microarray; and RNA-seq studies. Is affected by six chemicals including methylmercuric chloride; antimycin; and Doxycycline based on microarray and RNA-seq studies. Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS_history: T06D4.3:wp112
      T06D4.3:wp274
    Corresponding_pseudogene: T06D4.3
    Associated_feature: WBsf987235
      WBsf987236
      WBsf987237
      WBsf1011890
      WBsf222850
  Experimental_info: Expr_pattern: Expr1019775
      Expr1038838
      Expr1156243
    Drives_construct: WBCnstr00025238
    Construct_product: WBCnstr00025238
    Microarray_results (16)
    Expression_cluster (60)
    Interaction: WBInteraction000182886
      WBInteraction000185867
      WBInteraction000292594
      WBInteraction000324997
      WBInteraction000336145
      WBInteraction000354053
      WBInteraction000390552
      WBInteraction000432514
      WBInteraction000435350
      WBInteraction000448442
  Map_info: Map: II Position: -6.3161
    Positive: Positive_clone: T06D4 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene