WormBase Tree Display for Gene: WBGene00020269

WBGene00020269 SMap: S_parent: Sequence: T05H4
  Identity: Version: 3
    Name: CGC_name: erfa-1 Person_evidence: WBPerson124
      Sequence_name: T05H4.6
      Molecular_name: T05H4.6a
        T05H4.6a.1
        CE52351
        T05H4.6b
        CE13279
        T05H4.6b.1
        T05H4.6b.2
      Other_name: phi-21 Person_evidence: WBPerson2582
        etf-1 Person_evidence: WBPerson261
        CELE_T05H4.6 Accession_evidence: NDB BX284605
      Public_name: erfa-1
    DB_info: Database: AceView gene 5G915
        WormQTL gene WBGene00020269
        WormFlux gene WBGene00020269
        NDB locus_tag CELE_T05H4.6
        Panther gene CAEEL|WormBase=WBGene00020269|UniProtKB=O16520
          family PTHR10113
        NCBI gene 179028
        RefSeq protein NM_001356664.2
            NM_001392531.1
        SwissProt UniProtAcc O16520
        UniProt_GCRP UniProtAcc O16520
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:02 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 30 Sep 2011 16:40:15 WBPerson2970 Name_change: CGC_name: etf-1
        3 11 Nov 2013 09:06:04 WBPerson2970 Name_change: CGC_name: erfa-1
                Other_name: etf-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: erfa
    Allele (29)
    Strain: WBStrain00047473
    RNASeq_FPKM (74)
    GO_annotation: 00028225
      00028226
      00028227
      00028228
      00028229
      00028230
      00028231
      00028232
      00124940
      00124941
    Contained_in_operon: CEOP5112
    Ortholog (47)
    Structured_description: Automated_description: Predicted to enable sequence-specific mRNA binding activity and translation release factor activity, codon specific. Predicted to be involved in cytoplasmic translational termination. Predicted to be located in cytosol. Predicted to be part of translation release factor complex. Is an ortholog of human ETF1 (eukaryotic translation termination factor 1). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Molecular_info: Corresponding_CDS: T05H4.6a
      T05H4.6b
    Corresponding_CDS_history: T05H4.6:wp202
      T05H4.6a:wp142
      T05H4.6a:wp261
      T05H4.6b:wp142
    Corresponding_transcript: T05H4.6a.1
      T05H4.6b.1
      T05H4.6b.2
    Other_sequence (95)
    Associated_feature: WBsf646878
      WBsf655096
      WBsf1019802
      WBsf231875
      WBsf231876
      WBsf231877
      WBsf231878
  Experimental_info: RNAi_result (14)
    Expr_pattern: Expr1010817
      Expr1038825
      Expr1156207
      Expr2011356
      Expr2029592
    Drives_construct: WBCnstr00025250
    Construct_product: WBCnstr00025250
    Microarray_results (26)
    Expression_cluster: WBPaper00028451:Oogenic_protein
      WBPaper00031674:feh-1(gb561)(RNAi)_downregulated
      WBPaper00032425:up_in_zfp-1
      WBPaper00032528:L3_enriched
      WBPaper00033065:cyc-1(RNAi)_downregulated
      WBPaper00035269:cde-1_regulated
      WBPaper00036375:enriched_in_PVD_OLL
      WBPaper00037047:aging_accelerated_insoluble_protein
      WBPaper00037047:insoluble_protein
      WBPaper00037946:LIN-39_interacting
      WBPaper00038118:aak-2(gt33)_upregulated
      WBPaper00038118:stress_upregulated_N2
      WBPaper00038289:oocyte_protein
      WBPaper00043951:insoluble_protein_day16_N2
      WBPaper00044037:eat-2_downregulated
      WBPaper00044128:DietaryRestriction_downregulated
      WBPaper00044426:rotenone_24h_downregulated
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044746:aging_downregulated_HeatShock
      WBPaper00045417:128Q-huntingtin_downreglated
      WBPaper00045521:Gender_Neutral
      WBPaper00045571:germline-ablation_downregulated
      WBPaper00045774:clk-1_downregulated
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.1mix_downregulated_12h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_6h
      WBPaper00046497:B.thuringiensis_0.5mix_downregulated_12h
      WBPaper00046691:AB_enriched
      WBPaper00048910:mRNA-interacting_protein
      WBPaper00048988:neuron_expressed
      WBPaper00049545:cco-1(RNAi)_upregulated
      WBPaper00049545:jmjd-3.1(+)_upregulated
      WBPaper00049545:rgef-1p-jmjd-1.2(+)_upregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_upregulated
      WBPaper00049920:Glucose-Diet_downregulated_hyl-2(tm2031)
      WBPaper00049942:hsf-1(RNAi)_downregulated
      WBPaper00050015:ifg-1(RNAi)_downregulated
      WBPaper00050412:cco-1(RNAi)_upregulated_N2
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050636:aging_regulated_insoluble_protein
      WBPaper00050726:OsmoticStress_regulated_NoFood
      WBPaper00050726:starvation_regulated_LowSalt
      WBPaper00050859:downregulated_P-granule(-)GFP(+)_vs_control_day2-adult
      WBPaper00050859:downregulated_P-granule(-)GFP(-)_vs_control_day2-adult
      WBPaper00050990:hypodermis_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00051039:germline_enriched
      WBPaper00052884:emb-4(hc60)_downregulated
      WBPaper00053184:sma-2(rax5)_downregulated
      WBPaper00053184:sma-4(rax3)_downregulated
      WBPaper00053289:DREAM-target
      WBPaper00053388:dauer_regulated_Cluster1
      WBPaper00053615:SMO-1_target
      WBPaper00053810:clk-1(qm30)_downregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053810:isp-1(qm150)_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00053814:25C_downregulated_OP50
      WBPaper00053814:25C_downregulated_PY79
      WBPaper00055334:DLC-1_interacting
      WBPaper00055482:pmt-2(RNAi)_downregulated
      WBPaper00055648:germline_expressed
      WBPaper00056034:pals-22(jy3)_downregulated
      WBPaper00056034:pals-25(jy9)_downregulated
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056090:E.faecalis_downregulated_N2
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00056471:S.aureus-4h_downregulated_N2
      WBPaper00056809:smn-1(ok355)_downregulated
      WBPaper00056997:nmad-1(ok3133)_downregulated_germline_25C
      WBPaper00057288:Cold_downregulated_transcript
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058691:set-2(bn129)_downregulated
      WBPaper00059895:wounding_downregulated
      WBPaper00060014:set-2(tm1630)_upregulated
      WBPaper00060084:cco-1(RNAi)_downregulated_N2
      WBPaper00060358:B.thuringiensis_pathogen_regulated_elt-2(RNAi)
      WBPaper00060358:B.thuringiensis_pathogen_regulated_N2
      WBPaper00060459:bcat-1(RNAi)_downregulated
      WBPaper00060811:L1_vs_adult_downregulated_neural
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061341:28C_48h_downregulated
      WBPaper00061479:HDA-1_interacting_protein
      WBPaper00061527:tomm-40_3370-eif-3.C_3529
      WBPaper00061527:Y45F10D.7-C14C10.4
      WBPaper00062143:PQN-59_interacting
      WBPaper00062159:hda-2(ok1479)_downregulated
      WBPaper00062193:hsf-1(RNAi)_downregulated
      WBPaper00062193:skn-1(RNAi)_downregulated
      WBPaper00062325:muscle_depleted_coding-RNA
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00062554:MAGU-2_interacting
      WBPaper00062669:extracellular-vesicle_protein
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064201:SNA-3_interacting
      WBPaper00064315:mes-3(bn199)_downregulated_EGCs
      WBPaper00064315:mes-4(bn73)_downregulated_EGCs
      WBPaper00064315:mrg-1(qa6200)_downregulated_PGCs
      WBPaper00064494:postdauer_upregulated_AWA
      WBPaper00064532:pals-25(icb98)_downregulated
      WBPaper00064716:paraquat_upregulated
      WBPaper00064871:hypoxia_upregulated_F1
      WBPaper00065120:body-muscle-transcriptome
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065373:sek-1(km4)_downregulated_cisplatin
      WBPaper00065945:epidermis-rpoa-2(-)_downregulated_protein
      WBPaper00065975:P-body_vs_oocyte_depleted
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4489_group_3
      WBPaper00025032:cluster_30
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00025141:unc-4::GFP_Expressed_Genes
      WBPaper00026929:sir-2.1_overexpression_regulated
      WBPaper00029437:dcr-1_downregulated
      WBPaper00031003:24hr_muscle_depleted
      WBPaper00031003:total_muscle_depleted
      WBPaper00031532:Larva_Pan_Neuronal_Enriched
      WBPaper00031832:slr-2_regulated
      WBPaper00032948:FedUp
      WBPaper00034739:N2moreDR1350
      WBPaper00035905:FBF-1_Associated
      WBPaper00037901:GLD-1_mRNA_targets
      WBPaper00038060:SUMO-1_upregulated
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00040184:hcf-1nc_sir-2.1nc_daf-2down
      WBPaper00040210:Chlorpyrifos_24C_regulated
      WBPaper00040210:Chlorpyrifos_Diazinon_24C_regulated
      WBPaper00040426:CYD-1_CDK-4_downregulated
      WBPaper00040858:eQTL_age_regulated_developing
      WBPaper00040963:TA300_up
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00045263:isp-1(qm150)_downregulated
      WBPaper00045263:nuo-6(qm200)_downregulated
      WBPaper00045960:L1-L4-lethargus_downregulated
      WBPaper00045960:L4-lethargus_downregulated
      WBPaper00047070:N2_starvation_downregulated
      WBPaper00048637:lin-35(n745)_starvation_upregulated
      WBPaper00050520:lagr-1(gk327);hyl-1(ok976)_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      WBPaper00057098:SiO2-nanoparticles_upregulated
      [cgc5767]:expression_class_E
      [cgc5767]:expression_class_E_pi(101_min)
      [cgc5767]:expression_class_M
      [cgc5767]:expression_class_ME
    Interaction (281)
  Map_info: Map: V Position: -0.173758 Error: 0.001676
    Positive: Positive_clone: T05H4 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00033090
    WBPaper00035228
    WBPaper00038491
    WBPaper00046427
    WBPaper00049828
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene