WormBase Tree Display for Gene: WBGene00020007
expand all nodes | collapse all nodes | view schema
WBGene00020007 | SMap | S_parent | Sequence | R11F4 | |||
---|---|---|---|---|---|---|---|
Identity (6) | |||||||
Gene_info | Biotype | SO:0001217 | |||||
Allele (47) | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (19) | |||||||
Ortholog (45) | |||||||
Paralog | WBGene00011147 | Caenorhabditis elegans | From_analysis | Panther | |||
WormBase-Compara | |||||||
WBGene00012017 | Caenorhabditis elegans | From_analysis | Panther | ||||
WBGene00016939 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
Structured_description | Concise_description | The R11F4.1 gene encodes a putative glycerol kinase and is orthologous to human glycerol kinase (GK); glycerol kinase catalyses the phosphorylation of glycerol to glycerol-3 phosphate; in elegans, glycerol kinase is enriched in the dauer stage and is one of several genes involved in energy metabolism that are upregulated, when worms are grown in a nutrient deficient medium. | Paper_evidence | WBPaper00004103 | |||
WBPaper00031648 | |||||||
WBPaper00005859 | |||||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson567 | |||||||
Date_last_updated | 27 Aug 2012 00:00:00 | ||||||
Automated_description | Predicted to enable glycerol kinase activity. Predicted to be involved in glycerol metabolic process; phosphate-containing compound metabolic process; and triglyceride metabolic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in glycerol kinase deficiency. Is an ortholog of human GK (glycerol kinase); GK2 (glycerol kinase 2); and GK3 (glycerol kinase 3). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:0060363 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4289) | ||
Disease_relevance | R11F4.1 is orthologous to human glycerol kinase, which when mutated causes glycerol kinase deficiency, leading to hyperglycerolemia. | Homo sapiens | Accession_evidence | OMIM | 307030 | ||
300474 | |||||||
Curator_confirmed | WBPerson324 | ||||||
Date_last_updated | 27 Aug 2012 00:00:00 | ||||||
Molecular_info | Corresponding_CDS | R11F4.1 | |||||
Corresponding_transcript | R11F4.1.1 | ||||||
Other_sequence (158) | |||||||
Associated_feature (18) | |||||||
Experimental_info | RNAi_result | WBRNAi00001325 | Inferred_automatically | RNAi_primary | |||
WBRNAi00051795 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00001756 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00001439 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00017755 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00034863 | Inferred_automatically | RNAi_primary | |||||
Expr_pattern | Chronogram446 | ||||||
Expr6508 | |||||||
Expr1012336 | |||||||
Expr1038688 | |||||||
Expr1155456 | |||||||
Expr2005589 | |||||||
Expr2023807 | |||||||
Drives_construct | WBCnstr00003958 | ||||||
WBCnstr00025437 | |||||||
Construct_product | WBCnstr00025437 | ||||||
Microarray_results (23) | |||||||
Expression_cluster (225) | |||||||
Interaction (130) | |||||||
Map_info | Positive | Positive_clone | R11F4 | Inferred_automatically | From sequence, transcript, pseudogene data | ||
Interpolated_map_position | II | -5.62873 | |||||
Reference (4) | |||||||
Method | Gene |