WormBase Tree Display for Gene: WBGene00019960
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| WBGene00019960 | SMap | S_parent | Sequence | CHROMOSOME_X | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | ztf-16 | Person_evidence | WBPerson1997 | |||||
| Sequence_name | R08E3.4 | ||||||||
| Molecular_name | R08E3.4a | ||||||||
| R08E3.4a.1 | |||||||||
| CE37662 | |||||||||
| R08E3.4b | |||||||||
| CE37663 | |||||||||
| R08E3.4b.1 | |||||||||
| Other_name | CELE_R08E3.4 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | ztf-16 | ||||||||
| DB_info | Database | AceView | gene | XF426 | |||||
| WormQTL | gene | WBGene00019960 | |||||||
| WormFlux | gene | WBGene00019960 | |||||||
| NDB | locus_tag | CELE_R08E3.4 | |||||||
| NCBI | gene | 180756 | |||||||
| RefSeq | protein | NM_001029680.6 | |||||||
| NM_001029679.5 | |||||||||
| SwissProt | UniProtAcc | H2L008 | |||||||
| TREEFAM | TREEFAM_ID | TF317508 | |||||||
| UniProt_GCRP | UniProtAcc | H2L008 | |||||||
| OMIM | gene | 603023 | |||||||
| 606221 | |||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:02 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 18 Apr 2008 09:32:24 | WBPerson2970 | Name_change | CGC_name | ztf-16 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | ztf | ||||||||
| Allele (106) | |||||||||
| Strain | WBStrain00002035 | ||||||||
| WBStrain00032267 | |||||||||
| WBStrain00037213 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00022741 | ||||||||
| 00022742 | |||||||||
| 00022743 | |||||||||
| 00022744 | |||||||||
| 00022745 | |||||||||
| 00022746 | |||||||||
| 00022747 | |||||||||
| 00022748 | |||||||||
| 00022749 | |||||||||
| Ortholog (46) | |||||||||
| Paralog (13) | |||||||||
| Structured_description | Concise_description | ztf-16 encodes a hunchback/Ikaros-like C2H2 zinc finger transcription factor; ZTF-16 activity is required for remodeling of glial cells during dauer larval development; ZTF-16 regulates dauer-specific changes to amphid glial cell morphology through regulation of the expression of ver-1, which encodes a receptor tyrosine kinase. | Paper_evidence | WBPaper00040681 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 08 Apr 2014 00:00:00 | ||||||||
| Automated_description | Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in gonad development and positive regulation of gene expression. Located in nucleus. Expressed in accessory cell; gonad; hypodermis; and tail. Human ortholog(s) of this gene implicated in several diseases, including B-lymphoblastic leukemia/lymphoma; carcinoma (multiple); and common variable immunodeficiency 13. Is an ortholog of several human genes including IKZF1 (IKAROS family zinc finger 1); IKZF2 (IKAROS family zinc finger 2); and IKZF3 (IKAROS family zinc finger 3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:9256 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:13176) | ||||
| DOID:612 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:13178) | ||||||
| DOID:3908 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:13177,HGNC:13178) | ||||||
| DOID:9952 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:13176) | ||||||
| DOID:3910 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:13176) | ||||||
| DOID:0080630 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:13176) | ||||||
| DOID:0081155 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:13176) | ||||||
| DOID:0050685 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:13178) | ||||||
| DOID:684 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:13176) | ||||||
| Molecular_info | Corresponding_CDS | R08E3.4a | |||||||
| R08E3.4b | |||||||||
| Corresponding_CDS_history | R08E3.4:wp133 | ||||||||
| Corresponding_transcript | R08E3.4a.1 | ||||||||
| R08E3.4b.1 | |||||||||
| Other_sequence | Acan_isotig14476 | ||||||||
| CR03932 | |||||||||
| JI166988.1 | |||||||||
| JI164742.1 | |||||||||
| CRC12103_1 | |||||||||
| Dviv_isotig28189 | |||||||||
| Tcol_isotig14469 | |||||||||
| JI180311.1 | |||||||||
| Associated_feature (20) | |||||||||
| Transcription_factor | WBTranscriptionFactor000322 | ||||||||
| Experimental_info | RNAi_result | WBRNAi00051551 | Inferred_automatically | RNAi_primary | |||||
| Expr_pattern | Chronogram1092 | ||||||||
| Expr6484 | |||||||||
| Expr8873 | |||||||||
| Expr9934 | |||||||||
| Expr1013591 | |||||||||
| Expr1038670 | |||||||||
| Expr1155229 | |||||||||
| Expr2018189 | |||||||||
| Expr2036326 | |||||||||
| Drives_construct | WBCnstr00002819 | ||||||||
| WBCnstr00005957 | |||||||||
| WBCnstr00005958 | |||||||||
| WBCnstr00005959 | |||||||||
| WBCnstr00014943 | |||||||||
| WBCnstr00025465 | |||||||||
| Construct_product | WBCnstr00005957 | ||||||||
| WBCnstr00009944 | |||||||||
| WBCnstr00016479 | |||||||||
| WBCnstr00016608 | |||||||||
| WBCnstr00017947 | |||||||||
| WBCnstr00025465 | |||||||||
| Microarray_results (32) | |||||||||
| Expression_cluster (133) | |||||||||
| Interaction (98) | |||||||||
| Map_info | Map | X | Position | -6.22914 | Error | 0.003179 | |||
| Positive | Positive_clone | R08E3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (15) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
