WormBase Tree Display for Gene: WBGene00019875
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WBGene00019875 | SMap | S_parent | Sequence | R05C11 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | mca-2 | |||||||
Sequence_name | R05C11.3 | ||||||||
Molecular_name | R05C11.3 | ||||||||
R05C11.3.1 | |||||||||
CE28747 | |||||||||
Other_name | CELE_R05C11.3 | Accession_evidence | NDB | BX284604 | |||||
Public_name | mca-2 | ||||||||
DB_info | Database (13) | ||||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 28 May 2004 13:31:02 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
2 | 05 Feb 2009 12:16:59 | WBPerson2970 | Event | Acquires_merge | WBGene00003152 | ||||
Name_change | CGC_name | mca-2 | |||||||
Acquires_merge | WBGene00003152 | ||||||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | mca | ||||||||
Allele (137) | |||||||||
Legacy_information | [Kraev A] mca for Membrane Calcium ATPase. No mutants known. See mca-1. | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation | 00097511 | ||||||||
00097512 | |||||||||
00097513 | |||||||||
00097514 | |||||||||
00097515 | |||||||||
00097516 | |||||||||
00097517 | |||||||||
00097518 | |||||||||
00097519 | |||||||||
00097520 | |||||||||
00097521 | |||||||||
00097522 | |||||||||
00124630 | |||||||||
00124631 | |||||||||
00124632 | |||||||||
00124633 | |||||||||
00124634 | |||||||||
00124635 | |||||||||
00124636 | |||||||||
Ortholog (52) | |||||||||
Paralog (14) | |||||||||
Structured_description | Concise_description | mca-2 encodes a calcium-transporting ATPase; large-scale RNAi screens indicate that mca-2 activity is required for locomotion and normal rates of postembryonic growth. | Paper_evidence | WBPaper00005654 | |||||
WBPaper00006395 | |||||||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 16 Nov 2006 00:00:00 | ||||||||
Automated_description | Predicted to enable P-type calcium transporter activity. Predicted to be involved in regulation of cytosolic calcium ion concentration. Predicted to be located in intracellular membrane-bounded organelle. Expressed in hypodermis. Human ortholog(s) of this gene implicated in X-linked spinocerebellar ataxia 1; autosomal dominant intellectual developmental disorder; and nonsyndromic deafness (multiple). Is an ortholog of several human genes including ATP2B1 (ATPase plasma membrane Ca2+ transporting 1); ATP2B2 (ATPase plasma membrane Ca2+ transporting 2); and ATP2B3 (ATPase plasma membrane Ca2+ transporting 3). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Disease_info | Potential_model | DOID:0060307 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:814) | ||||
DOID:0111829 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:816) | ||||||
DOID:0050564 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:815) | ||||||
DOID:0110467 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:815) | ||||||
DOID:11714 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:814,HGNC:815,HGNC:816,HGNC:817) | ||||||
DOID:10591 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:814,HGNC:815,HGNC:816,HGNC:817) | ||||||
Molecular_info | Corresponding_CDS | R05C11.3 | |||||||
Corresponding_transcript | R05C11.3.1 | ||||||||
Other_sequence (62) | |||||||||
Associated_feature | WBsf659962 | ||||||||
WBsf995618 | |||||||||
WBsf995619 | |||||||||
WBsf995620 | |||||||||
WBsf995621 | |||||||||
WBsf1016855 | |||||||||
WBsf1016856 | |||||||||
WBsf1016857 | |||||||||
WBsf1016858 | |||||||||
WBsf227999 | |||||||||
Experimental_info | RNAi_result | WBRNAi00051265 | Inferred_automatically | RNAi_primary | |||||
WBRNAi00027426 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00026020 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00066745 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00066559 | Inferred_automatically | RNAi_primary | |||||||
WBRNAi00017425 | Inferred_automatically | RNAi_primary | |||||||
Expr_pattern | Expr8319 | ||||||||
Expr1013470 | |||||||||
Expr1038621 | |||||||||
Expr1154966 | |||||||||
Expr2013443 | |||||||||
Expr2031677 | |||||||||
Drives_construct | WBCnstr00008392 | ||||||||
Microarray_results (20) | |||||||||
Expression_cluster (173) | |||||||||
Interaction (38) | |||||||||
Map_info | Map | IV | Position | -11.4549 | Error | 0.132104 | |||
Positive | Positive_clone | R05C11 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference | WBPaper00003407 | ||||||||
WBPaper00038491 | |||||||||
WBPaper00055090 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |