ger-1 encodes the C. elegans ortholog of GDP-keto-6-deoxymannose 3,5-epimerase/4-reductase; GER-1 is involved in the synthesis of GDP-fucose and exhibits enzymatic activity in vitro; ger-1 is expressed in larvae and adults.
Enables GDP-L-fucose synthase activity. Involved in GDP-L-fucose biosynthetic process. Expressed in pharynx; seam cell; and spermatheca. Is an ortholog of human GFUS (GDP-L-fucose synthase).
Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.