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WormBase Tree Display for Gene: WBGene00019476

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Name Class

WBGene00019476SMapS_parentSequenceK07C11
Identity (6)
Gene_infoBiotypeSO:0001217
Gene_classtimp
Allele (15)
StrainWBStrain00051251
RNASeq_FPKM (74)
GO_annotation00071022
00071023
00071024
00071025
00071026
00071027
00071028
00124320
Ortholog (27)
ParalogWBGene00019478Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionAutomated_descriptionPredicted to enable metalloendopeptidase inhibitor activity and protease binding activity. Predicted to be involved in negative regulation of membrane protein ectodomain proteolysis and response to organic substance. Predicted to be located in extracellular matrix and extracellular space. Expressed in several structures, including coelomocyte; gonad; head neurons; nerve ring; and vulval cell. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Duchenne muscular dystrophy; Huntington's disease; artery disease (multiple); and carcinoma (multiple). Is an ortholog of human TIMP2 (TIMP metallopeptidase inhibitor 2).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_model (16)
Molecular_infoCorresponding_CDSK07C11.3
Corresponding_transcriptK07C11.3.1
Other_sequenceCJC14055_1
Associated_featureWBsf646992
WBsf232076
Experimental_infoRNAi_resultWBRNAi00050122Inferred_automaticallyRNAi_primary
WBRNAi00034052Inferred_automaticallyRNAi_primary
WBRNAi00016701Inferred_automaticallyRNAi_primary
Expr_patternExpr14699
Expr14701
Expr1012009
Expr1038413
Expr1153823
Expr2004845
Expr2023066
Drives_construct (3)
Construct_productWBCnstr00025812
WBCnstr00040773
Microarray_results (20)
Expression_cluster (157)
Interaction (125)
Map_infoMapVPosition1.20444
PositivePositive_cloneK07C11Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00056623
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene