WormBase Tree Display for Gene: WBGene00019476

WBGene00019476 SMap: S_parent: Sequence: K07C11
  Identity: Version: 2
    Name: CGC_name: timp-1 Person_evidence: WBPerson2644
      Sequence_name: K07C11.3
      Molecular_name: K07C11.3
        K07C11.3.1
        CE29510
      Other_name: CELE_K07C11.3 Accession_evidence: NDB BX284605
      Public_name: timp-1
    DB_info: Database: AceView gene 5I687
        WormQTL gene WBGene00019476
        WormFlux gene WBGene00019476
        NDB locus_tag CELE_K07C11.3
        Panther gene CAEEL|WormBase=WBGene00019476|UniProtKB=Q21267
          family PTHR11844
        NCBI gene 179199
        RefSeq protein NM_072714.8
        TREEFAM TREEFAM_ID TF317409
        TrEMBL UniProtAcc Q21267
        UniProt_GCRP UniProtAcc Q21267
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:01 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 05 Sep 2017 13:25:30 WBPerson2970 Name_change: CGC_name: timp-1
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: timp
    Allele (15)
    Strain: WBStrain00051251
    RNASeq_FPKM (74)
    GO_annotation: 00071022
      00071023
      00071024
      00071025
      00071026
      00071027
      00071028
      00124320
    Ortholog (27)
    Paralog: WBGene00019478 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Automated_description: Predicted to enable metalloendopeptidase inhibitor activity and protease binding activity. Predicted to be involved in negative regulation of membrane protein ectodomain proteolysis and response to organic substance. Predicted to be located in extracellular matrix and extracellular space. Expressed in several structures, including coelomocyte; gonad; head neurons; nerve ring; and vulval cell. Human ortholog(s) of this gene implicated in several diseases, including Alzheimer's disease; Duchenne muscular dystrophy; Huntington's disease; artery disease (multiple); and carcinoma (multiple). Is an ortholog of human TIMP2 (TIMP metallopeptidase inhibitor 2). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model (16)
  Molecular_info: Corresponding_CDS: K07C11.3
    Corresponding_transcript: K07C11.3.1
    Other_sequence: CJC14055_1
    Associated_feature: WBsf646992
      WBsf232076
  Experimental_info: RNAi_result: WBRNAi00050122 Inferred_automatically: RNAi_primary
      WBRNAi00034052 Inferred_automatically: RNAi_primary
      WBRNAi00016701 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr14699
      Expr14701
      Expr1012009
      Expr1038413
      Expr1153823
      Expr2004845
      Expr2023066
    Drives_construct: WBCnstr00025812
      WBCnstr00040773
      WBCnstr00040776
    Construct_product: WBCnstr00025812
      WBCnstr00040773
    Microarray_results (20)
    Expression_cluster (157)
    Interaction: WBInteraction000139266
      WBInteraction000145496
      WBInteraction000150349
      WBInteraction000186575
      WBInteraction000198849
      WBInteraction000199491
      WBInteraction000201193
      WBInteraction000204619
      WBInteraction000210891
      WBInteraction000211002
      WBInteraction000212797
      WBInteraction000213571
      WBInteraction000214461
      WBInteraction000221068
      WBInteraction000225773
      WBInteraction000227834
      WBInteraction000229572
      WBInteraction000233429
      WBInteraction000234085
      WBInteraction000234721
      WBInteraction000234753
      WBInteraction000235569
      WBInteraction000238707
      WBInteraction000243093
      WBInteraction000249700
      WBInteraction000250514
      WBInteraction000251539
      WBInteraction000251984
      WBInteraction000252250
      WBInteraction000253444
      WBInteraction000256016
      WBInteraction000259058
      WBInteraction000259524
      WBInteraction000261841
      WBInteraction000262222
      WBInteraction000263224
      WBInteraction000269879
      WBInteraction000270981
      WBInteraction000275728
      WBInteraction000276952
      WBInteraction000280094
      WBInteraction000280183
      WBInteraction000281414
      WBInteraction000285717
      WBInteraction000289748
      WBInteraction000290363
      WBInteraction000292401
      WBInteraction000293416
      WBInteraction000295036
      WBInteraction000296424
      WBInteraction000296676
      WBInteraction000296776
      WBInteraction000297280
      WBInteraction000298512
      WBInteraction000298679
      WBInteraction000299878
      WBInteraction000301623
      WBInteraction000302106
      WBInteraction000303501
      WBInteraction000306547
      WBInteraction000308264
      WBInteraction000308643
      WBInteraction000309059
      WBInteraction000310279
      WBInteraction000312014
      WBInteraction000313973
      WBInteraction000316883
      WBInteraction000318493
      WBInteraction000321905
      WBInteraction000324534
      WBInteraction000324873
      WBInteraction000326177
      WBInteraction000327749
      WBInteraction000330612
      WBInteraction000332685
      WBInteraction000333042
      WBInteraction000335861
      WBInteraction000336885
      WBInteraction000337154
      WBInteraction000337415
      WBInteraction000337983
      WBInteraction000339493
      WBInteraction000347829
      WBInteraction000348960
      WBInteraction000352765
      WBInteraction000354334
      WBInteraction000358712
      WBInteraction000360993
      WBInteraction000361160
      WBInteraction000363272
      WBInteraction000369439
      WBInteraction000376424
      WBInteraction000381458
      WBInteraction000381903
      WBInteraction000383597
      WBInteraction000388783
      WBInteraction000389344
      WBInteraction000390202
      WBInteraction000394572
      WBInteraction000400235
      WBInteraction000401155
      WBInteraction000407492
      WBInteraction000408554
      WBInteraction000410155
      WBInteraction000416689
      WBInteraction000418311
      WBInteraction000421947
      WBInteraction000422592
      WBInteraction000425945
      WBInteraction000426962
      WBInteraction000427759
      WBInteraction000428625
      WBInteraction000428950
      WBInteraction000434423
      WBInteraction000437866
      WBInteraction000438795
      WBInteraction000439444
      WBInteraction000443232
      WBInteraction000444578
      WBInteraction000452400
      WBInteraction000455133
      WBInteraction000456909
      WBInteraction000457425
      WBInteraction000457598
      WBInteraction000461016
  Map_info: Map: V Position: 1.20444
    Positive: Positive_clone: K07C11 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00056623
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene