WormBase Tree Display for Gene: WBGene00019473
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| WBGene00019473 | SMap | S_parent | Sequence | K07C6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | cyp-35A5 | |||||||
| Sequence_name | K07C6.5 | ||||||||
| Molecular_name | K07C6.5 | ||||||||
| K07C6.5.1 | |||||||||
| CE17176 | |||||||||
| Other_name | CELE_K07C6.5 | Accession_evidence | NDB | BX284605 | |||||
| Public_name | cyp-35A5 | ||||||||
| DB_info | Database | AceView | gene | 5E415 | |||||
| WormQTL | gene | WBGene00019473 | |||||||
| WormFlux | gene | WBGene00019473 | |||||||
| NDB | locus_tag | CELE_K07C6.5 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00019473|UniProtKB=O44649 | |||||||
| family | PTHR24300 | ||||||||
| NCBI | gene | 178802 | |||||||
| RefSeq | protein | NM_071691.7 | |||||||
| TrEMBL | UniProtAcc | O44649 | |||||||
| UniProt_GCRP | UniProtAcc | O44649 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:01 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 21 Sep 2004 09:38:16 | WBPerson1971 | Name_change | CGC_name | cyp-35A5 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cyp | ||||||||
| Allele (101) | |||||||||
| Strain | WBStrain00032308 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (16) | |||||||||
| Ortholog (163) | |||||||||
| Paralog (44) | |||||||||
| Structured_description | Concise_description | cyp-35A5 encodes one of over 80 C. elegans cytochrome P450s, NADPH-dependent monooxygenases that metabolize endogenous and exogenous compounds; RT-PCR experiments indicate that cyp-35A5 mRNA is upregulated in response to treatment with xenobiotics, such as PCBs (polychlorinated biphenyls) or PAHs (polycyclic aromatic hydrocarbons); loss of cyp-35A/C gene family activity in the presence of xenobiotics can diminish the reproductive decline seen in wild-type worms treated with the same compounds; in addition, cyp-35A(RNAi) also results in a reduction of fat content. | Paper_evidence | WBPaper00005655 | |||||
| WBPaper00025207 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 26 Feb 2009 00:00:00 | ||||||||
| Automated_description | Predicted to enable heme binding activity; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; and steroid hydroxylase activity. Involved in response to xenobiotic stimulus. Predicted to be located in cytoplasm and intracellular membrane-bounded organelle. Expressed in intestine. | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | K07C6.5 | |||||||
| Corresponding_transcript | K07C6.5.1 | ||||||||
| Other_sequence | EY465213.1 | ||||||||
| Oden_isotig19747 | |||||||||
| FC544809.1 | |||||||||
| Associated_feature | WBsf646730 | ||||||||
| WBsf231615 | |||||||||
| Experimental_info | RNAi_result (12) | ||||||||
| Expr_pattern | Expr11594 | ||||||||
| Expr1038412 | |||||||||
| Expr1153844 | |||||||||
| Expr2010738 | |||||||||
| Expr2028975 | |||||||||
| Drives_construct | WBCnstr00018362 | ||||||||
| WBCnstr00019075 | |||||||||
| WBCnstr00025813 | |||||||||
| Construct_product | WBCnstr00019075 | ||||||||
| WBCnstr00025813 | |||||||||
| Microarray_results (15) | |||||||||
| Expression_cluster (296) | |||||||||
| Interaction (28) | |||||||||
| Map_info | Map | V | Position | -7.49692 | Error | 0.002597 | |||
| Positive | Positive_clone | K07C6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (16) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
