WormBase Tree Display for Gene: WBGene00019275

WBGene00019275 SMap: S_parent: Sequence: H43I07
  Identity: Version: 2
    Name: CGC_name: rpac-40 Person_evidence: WBPerson10054
      Sequence_name: H43I07.2
      Molecular_name: H43I07.2
        H43I07.2.1
        CE29979
      Other_name: CELE_H43I07.2 Accession_evidence: NDB BX284605
      Public_name: rpac-40
    DB_info: Database (11)
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:01 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 28 Sep 2012 14:29:00 WBPerson2970 Name_change: CGC_name: rpac-40
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: rpac
    Allele (100)
    Strain: WBStrain00037571
    RNASeq_FPKM (74)
    GO_annotation (12)
    Contained_in_operon: CEOP5048
    Ortholog (38)
    Paralog: WBGene00007971 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
      WBGene00044614 Caenorhabditis elegans From_analysis: WormBase-Compara
    Structured_description: Automated_description: Predicted to enable DNA-directed 5'-3' RNA polymerase activity and protein dimerization activity. Predicted to contribute to RNA polymerase I activity and RNA polymerase III activity. Predicted to be involved in transcription by RNA polymerase I and transcription by RNA polymerase III. Predicted to be part of RNA polymerase I complex and RNA polymerase III complex. Human ortholog(s) of this gene implicated in Treacher Collins syndrome 3 and hypomyelinating leukodystrophy 11. Is an ortholog of human POLR1C (RNA polymerase I and III subunit C). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:0080791 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:20194)
      DOID:0060792 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:20194)
  Molecular_info: Corresponding_CDS: H43I07.2
    Corresponding_transcript: H43I07.2.1
    Other_sequence (61)
    Associated_feature: WBsf231653
  Experimental_info: RNAi_result (14)
    Expr_pattern: Expr1014630
      Expr1038328
      Expr1153290
      Expr2015418
      Expr2033653
    Microarray_results (18)
    Expression_cluster: WBPaper00005700:secreted_protein
      WBPaper00031040:TGF-beta_adult_downregulated
      WBPaper00037950:bodywall-muscle_larva_enriched
      WBPaper00041072:UTX-1_interacting_protein
      WBPaper00044501:gld-1_let-7_regulated
      WBPaper00044656:tatn-1(qd182)_downregulated
      WBPaper00044736:flat_dev_expression
      WBPaper00044746:aging_downregulated_HeatShock
      WBPaper00045521:Gender_Neutral
      WBPaper00048988:neuron_expressed
      WBPaper00049545:cco-1(RNAi)_downregulated
      WBPaper00049545:jmjd-3.1(+)_downregulated
      WBPaper00049545:sur-5p-jmjd-1.2(+)_downregulated
      WBPaper00049626:UNC-75_target
      WBPaper00050488:adult_vs_dauer_regulated_N2_20C
      WBPaper00050488:mir-34(gk437)_vs_mir-34(OverExpression)_regulated_dauer_20C
      WBPaper00050488:N2_vs_mir-34(gk437)_regulated_dauer_20C
      WBPaper00050686:glp-1(e2141)_downregulated
      WBPaper00050990:arcade_intestinal-valve_expressed
      WBPaper00050990:intestine_expressed
      WBPaper00051039:germline_enriched
      WBPaper00051245:body-wall-muscle_nucleus_expressed
      WBPaper00051245:epidermis_cytoplasm_expressed
      WBPaper00051245:epidermis_nucleus_expressed
      WBPaper00051245:intestine_cytoplasm_expressed
      WBPaper00051245:intestine_nucleus_expressed
      WBPaper00051245:nucleus_specific
      WBPaper00053302:stavudine_24h_regulated
      WBPaper00053388:dauer_regulated_Cluster2
      WBPaper00053599:oocyte_vs_mitosis_upregulated
      WBPaper00053810:daf-2(e1370)_downregulated
      WBPaper00053810:nuo-6(qm200)_downregulated
      WBPaper00055354:Rifampicin-Allantoin_upregulated
      WBPaper00055648:germline_expressed
      WBPaper00056090:E.faecalis_downregulated_hpx-2(dg047)
      WBPaper00056139:soil-microbiota_downregulated
      WBPaper00056443:sek-1(km4)_downregulated
      WBPaper00056471:aak-1(tm1944);aak-2(ok524)_downregulated
      WBPaper00057288:iff-1(RNAi)_downregulated_transcript
      WBPaper00058691:cfp-1(tm6369)_upregulated
      WBPaper00058691:sin-3(tm1276)_upregulated
      WBPaper00059254:CSR-1_interacting
      WBPaper00059254:PRG-1_interacting
      WBPaper00059328:mrps-5(RNAi)_downregulated_protein
      WBPaper00059605:MUT-16_interacting
      WBPaper00061341:28C_24h_downregulated
      WBPaper00061479:HDA-1_interacting_protein
      WBPaper00061527:trm-1-H43I07.2
      WBPaper00062123:DEPS-1_interacting
      WBPaper00062193:skn-1(RNAi)_upregulated
      WBPaper00062325:muscle_enriched_coding-RNA
      WBPaper00062498:PPM-1.D_interacting
      WBPaper00062554:MAGU-2_interacting
      WBPaper00064005:starvation_upregulated_N2_mRNA
      WBPaper00064071:NHR-49_interacting
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-1-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_daf-16(mu86);glp-1(e2141)
      WBPaper00064088:Day-3-adult_vs_L4_downregulated_glp-1(e2141)
      WBPaper00064315:mes-4(bn73)_downregulated_EGCs
      WBPaper00064716:paraquat_upregulated
      WBPaper00065258:anchor-cell_depleted
      WBPaper00065373:Cisplatin_downregulated_WT
      WBPaper00065945:epidermis-rpoa-2(-)_downregulated_protein
      WBPaper00065993:glp-1(e2141)_downregulated
      WBPaper00066146:germline-inx-14(RNAi)_downregulated_PA14
      cgc4489_group_2
      WBPaper00025032:cluster_189
      WBPaper00025141:N2_Expressed_Genes
      WBPaper00034757:down_by_oxidative_stress
      WBPaper00035905:FBF-1_Associated
      WBPaper00036286:Pattern_H
      WBPaper00038231:Cry5B_1.5-fold_downregulated
      WBPaper00041002:HF_3d_2.0mM_Down
      WBPaper00041606:CE_B.thuringiensis-DB27_regulated
      WBPaper00041606:CE_X.nematophila_regulated
      WBPaper00045263:0.1mM-paraquat_upregulated
      WBPaper00053236:Starvation_regulated_GR1307
      WBPaper00053236:Starvation_regulated_N2
      [cgc6390]:Cluster_F
      [cgc6390]:intrinsic
    Interaction (309)
  Map_info: Map: V Position: -6.30393
    Positive: Positive_clone: H43I07 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene