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WormBase Tree Display for Gene: WBGene00018900

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Name Class

WBGene00018900EvidencePerson_evidenceWBPerson2829
SMapS_parentSequenceF55G1
IdentityVersion1
NameCGC_namerod-1Person_evidenceWBPerson1816
WBPerson1836
Sequence_nameF55G1.4
Molecular_nameF55G1.4
F55G1.4.1
CE07281
Other_nameCELE_F55G1.4Accession_evidenceNDBBX284604
Public_namerod-1
DB_infoDatabaseAceViewgene4I249
WormQTLgeneWBGene00018900
WormFluxgeneWBGene00018900
NDBlocus_tagCELE_F55G1.4
PanthergeneCAEEL|WormBase=WBGene00018900|UniProtKB=Q20849
familyPTHR15688
NCBIgene177520
RefSeqproteinNM_068799.8
SwissProtUniProtAccQ20849
TREEFAMTREEFAM_IDTF101176
UniProt_GCRPUniProtAccQ20849
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:00WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classrod
Allele (86)
RNASeq_FPKM (74)
GO_annotation (29)
Ortholog (37)
Structured_descriptionConcise_descriptionrod-1 encodes a novel protein that is orthologous to the Drosophila Rough Deal and mammalian KNTC1 kinetochore components; in C. elegans, ROD-1 functions as part of the RZZ (Rod/Zw10/Zwilch) complex that regulates microtubule attachment to the kinetochores; ROD-1 physically interacts with, and negatively regulates activity of, NDC-80, a member of the NDC80 complex that mediates end-coupled microtubule attchament to kinetochores, thus ensuring correct temporal regulation of the transition from dynein-mediated, lateral microtuble attachments to NDC-80-mediated end-coupled attachments.Paper_evidenceWBPaper00032153
WBPaper00044471
Curator_confirmedWBPerson1843
Date_last_updated18 Nov 2013 00:00:00
Automated_descriptionEnables protein domain specific binding activity. Involved in several processes, including chromosome organization; positive regulation of kinetochore assembly; and regulation of cell cycle process. Part of RZZ complex. Is an ortholog of human KNTC1 (kinetochore associated 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF55G1.4
Corresponding_transcriptF55G1.4.1
Other_sequenceCBC03914_1
CBC12160_1
CJC11400_1
Associated_featureWBsf646081
WBsf660298
WBsf228536
WBsf228537
Experimental_infoRNAi_resultWBRNAi00084112Inferred_automaticallyRNAi_primary
WBRNAi00084070Inferred_automaticallyRNAi_primary
WBRNAi00084063Inferred_automaticallyRNAi_primary
WBRNAi00048542Inferred_automaticallyRNAi_primary
WBRNAi00084099Inferred_automaticallyRNAi_primary
WBRNAi00002411Inferred_automaticallyRNAi_primary
WBRNAi00084106Inferred_automaticallyRNAi_primary
Expr_patternExpr14570
Expr14571
Expr14572
Expr1010552
Expr1038157
Expr1152327
Expr2015401
Expr2033635
Drives_constructWBCnstr00026202
WBCnstr00039330
Construct_productWBCnstr00026202
WBCnstr00039330
AntibodyWBAntibody00002750
Microarray_results (20)
Expression_cluster (187)
Interaction (25)
Map_infoMapIVPosition3.33774Error6.6e-05
PositivePositive_cloneF55G1Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00027235
WBPaper00032153
WBPaper00032519
WBPaper00038491
WBPaper00044471
WBPaper00055090
WBPaper00055650
WBPaper00060892
WBPaper00063102
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene