WormBase Tree Display for Gene: WBGene00018783
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| WBGene00018783 | SMap | S_parent | Sequence | F54A3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | cbs-2 | Paper_evidence | WBPaper00039977 | |||||
| Person_evidence | WBPerson537 | ||||||||
| Sequence_name | F54A3.4 | ||||||||
| Molecular_name | F54A3.4 | ||||||||
| F54A3.4.1 | |||||||||
| CE47819 | |||||||||
| Other_name | F54A3.d | Curator_confirmed | WBPerson1983 | ||||||
| Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
| F54A3.e | Curator_confirmed | WBPerson1983 | |||||||
| Remark | Old cosmid naming mapped via unique overlapping PCR_product on CDSs | ||||||||
| CELE_F54A3.4 | Accession_evidence | NDB | BX284602 | ||||||
| Public_name | cbs-2 | ||||||||
| DB_info | Database (13) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:00 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 29 Sep 2011 10:45:56 | WBPerson2970 | Name_change | CGC_name | cbs-2 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | cbs | ||||||||
| Allele (177) | |||||||||
| Strain | WBStrain00031552 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (11) | |||||||||
| Contained_in_operon | CEOP2708 | ||||||||
| Ortholog (23) | |||||||||
| Paralog (12) | |||||||||
| Structured_description | Concise_description | The F54A3.4 gene encodes a homolog of the human gene CBS, which when mutated leads to homocystinuria (OMIM:236200). | Paper_evidence | WBPaper00004637 | |||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 17 Jun 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable cystathionine beta-synthase activity. Predicted to be involved in cysteine biosynthetic process from serine. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including homocystinuria; hyperhomocysteinemia; and neural tube defect. Is an ortholog of human CBS (cystathionine beta-synthase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0080074 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||
| DOID:12365 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||||
| DOID:9279 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||||
| DOID:9263 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||||
| DOID:3526 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||||
| DOID:3393 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:1550) | ||||||
| Molecular_info | Corresponding_CDS | F54A3.4 | |||||||
| Corresponding_CDS_history | F54A3.4:wp233 | ||||||||
| Corresponding_transcript | F54A3.4.1 | ||||||||
| Other_sequence (18) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00048206 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00015558 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00048207 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00015557 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr1026794 | ||||||||
| Expr1038097 | |||||||||
| Expr1152016 | |||||||||
| Expr2009745 | |||||||||
| Expr2027985 | |||||||||
| Microarray_results (12) | |||||||||
| Expression_cluster (167) | |||||||||
| Interaction (85) | |||||||||
| Map_info | Map | II | Position | -13.8397 | Error | 0.00061 | |||
| Positive | Positive_clone | F54A3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00039977 | |||||||||
| WBPaper00040475 | |||||||||
| WBPaper00040626 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00059856 | |||||||||
| WBPaper00060693 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
