WormBase Tree Display for Gene: WBGene00018718
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| WBGene00018718 | SMap | S_parent | Sequence | F52H2 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | dhcr-24 | Person_evidence | WBPerson3851 | |||||
| Sequence_name | F52H2.6 | ||||||||
| Molecular_name | F52H2.6a | ||||||||
| F52H2.6a.1 | |||||||||
| CE10874 | |||||||||
| F52H2.6b | |||||||||
| CE53604 | |||||||||
| F52H2.6b.1 | |||||||||
| Other_name | CELE_F52H2.6 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | dhcr-24 | ||||||||
| DB_info | Database | AceView | gene | XD178 | |||||
| WormQTL | gene | WBGene00018718 | |||||||
| WormFlux | gene | WBGene00018718 | |||||||
| NDB | locus_tag | CELE_F52H2.6 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00018718|UniProtKB=O17397 | |||||||
| family | PTHR10801 | ||||||||
| NCBI | gene | 186134 | |||||||
| RefSeq | protein | NM_076062.8 | |||||||
| NM_001374978.3 | |||||||||
| SwissProt | UniProtAcc | O17397 | |||||||
| TrEMBL | UniProtAcc | A0A5E4LZ56 | |||||||
| UniProt_GCRP | UniProtAcc | O17397 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:00 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 15 Oct 2019 15:58:06 | WBPerson1983 | Name_change | CGC_name | dhcr-24 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | dhcr | ||||||||
| Allele (73) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00004066 | ||||||||
| 00004067 | |||||||||
| 00029731 | |||||||||
| 00029732 | |||||||||
| 00029733 | |||||||||
| 00123762 | |||||||||
| Ortholog (33) | |||||||||
| Paralog | WBGene00012407 | Caenorhabditis elegans | From_analysis | Panther | |||||
| WormBase-Compara | |||||||||
| Structured_description | Concise_description | F52H2.6 is orthologous to the human gene 3BETA-HYDROXYSTEROL DELTA 24 REDUCTASE (DHCR24; OMIM:606418), which when mutated leads to disease. | Curator_confirmed | WBPerson1823 | |||||
| WBPerson567 | |||||||||
| Date_last_updated | 06 Aug 2004 00:00:00 | ||||||||
| Automated_description | Predicted to enable delta24(24-1) sterol reductase activity. Predicted to be involved in steroid metabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in lipid metabolism disorder. Is an ortholog of human DHCR24 (24-dehydrocholesterol reductase). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:3146 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:2859) | ||||
| Molecular_info | Corresponding_CDS | F52H2.6a | |||||||
| F52H2.6b | |||||||||
| Corresponding_transcript | F52H2.6a.1 | ||||||||
| F52H2.6b.1 | |||||||||
| Other_sequence (19) | |||||||||
| Associated_feature | WBsf670205 | ||||||||
| WBsf716847 | |||||||||
| WBsf237096 | |||||||||
| WBsf237097 | |||||||||
| Experimental_info | RNAi_result | WBRNAi00015439 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00048026 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00032640 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr15161 | ||||||||
| Expr1014916 | |||||||||
| Expr1038059 | |||||||||
| Expr1151844 | |||||||||
| Expr2004013 | |||||||||
| Expr2022235 | |||||||||
| Drives_construct | WBCnstr00026318 | ||||||||
| Construct_product | WBCnstr00026318 | ||||||||
| Microarray_results (18) | |||||||||
| Expression_cluster (129) | |||||||||
| Interaction (15) | |||||||||
| Map_info | Map | X | Position | -14.3903 | |||||
| Positive | Positive_clone | F52H2 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00042257 | |||||||||
| WBPaper00055090 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
