WormBase Tree Display for Gene: WBGene00018718

WBGene00018718 SMap: S_parent: Sequence: F52H2
  Identity: Version: 2
    Name: CGC_name: dhcr-24 Person_evidence: WBPerson3851
      Sequence_name: F52H2.6
      Molecular_name: F52H2.6a
        F52H2.6a.1
        CE10874
        F52H2.6b
        CE53604
        F52H2.6b.1
      Other_name: CELE_F52H2.6 Accession_evidence: NDB BX284606
      Public_name: dhcr-24
    DB_info: Database: AceView gene XD178
        WormQTL gene WBGene00018718
        WormFlux gene WBGene00018718
        NDB locus_tag CELE_F52H2.6
        Panther gene CAEEL|WormBase=WBGene00018718|UniProtKB=O17397
          family PTHR10801
        NCBI gene 186134
        RefSeq protein NM_076062.8
            NM_001374978.3
        SwissProt UniProtAcc O17397
        TrEMBL UniProtAcc A0A5E4LZ56
        UniProt_GCRP UniProtAcc O17397
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:31:00 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
        2 15 Oct 2019 15:58:06 WBPerson1983 Name_change: CGC_name: dhcr-24
    Status: Live
  Gene_info: Biotype: SO:0001217
    Gene_class: dhcr
    Allele (73)
    RNASeq_FPKM (74)
    GO_annotation: 00004066
      00004067
      00029731
      00029732
      00029733
      00123762
    Ortholog: WBGene00025213 Caenorhabditis briggsae From_analysis: Hillier-set
            OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00058175 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00150301 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00125435 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00161239 Caenorhabditis brenneri From_analysis: TreeFam
      WBGene00126372 Caenorhabditis japonica From_analysis: TreeFam
      WBGene00058693 Caenorhabditis remanei From_analysis: TreeFam
      CBOVI.g3424 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g10897 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g12645 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP28.g18877 Caenorhabditis panamensis From_analysis: WormBase-Compara
      CSP29.g15716 Caenorhabditis becei From_analysis: WormBase-Compara
      CSP31.g21892 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP32.g16630 Caenorhabditis sulstoni From_analysis: WormBase-Compara
      CSP38.g13070 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP39.g1300 Caenorhabditis waitukubuli From_analysis: WormBase-Compara
      CSP40.g12522 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00033.g1913 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cnig_chr_X.g23028 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold582.g4634 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00066.g3155 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_01010 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_023887 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g08598 Oscheius tipulae From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g13968 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g1094 Panagrellus redivivus From_analysis: WormBase-Compara
      Sp34_X0099610 Caenorhabditis inopinata From_analysis: WormBase-Compara
      chrX_pilon.g18636 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00112356 Pristionchus pacificus From_analysis: WormBase-Compara
      ZFIN:ZDB-GENE-041212-73 Danio rerio From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      HGNC:2859 Homo sapiens From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      MGI:1922004 Mus musculus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
      RGD:1306529 Rattus norvegicus From_analysis: EnsEMBL-Compara
            Hieranoid
            Inparanoid
            OMA
            OrthoFinder
            OrthoInspector
            Panther
            PhylomeDB
            SonicParanoid
    Paralog: WBGene00012407 Caenorhabditis elegans From_analysis: Panther
            WormBase-Compara
    Structured_description: Concise_description: F52H2.6 is orthologous to the human gene 3BETA-HYDROXYSTEROL DELTA 24 REDUCTASE (DHCR24; OMIM:606418), which when mutated leads to disease. Curator_confirmed: WBPerson1823
            WBPerson567
          Date_last_updated: 06 Aug 2004 00:00:00
      Automated_description: Predicted to enable delta24(24-1) sterol reductase activity. Predicted to be involved in steroid metabolic process. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in lipid metabolism disorder. Is an ortholog of human DHCR24 (24-dehydrocholesterol reductase). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:3146 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:2859)
  Molecular_info: Corresponding_CDS: F52H2.6a
      F52H2.6b
    Corresponding_transcript: F52H2.6a.1
      F52H2.6b.1
    Other_sequence (19)
    Associated_feature: WBsf670205
      WBsf716847
      WBsf237096
      WBsf237097
  Experimental_info: RNAi_result: WBRNAi00015439 Inferred_automatically: RNAi_primary
      WBRNAi00048026 Inferred_automatically: RNAi_primary
      WBRNAi00032640 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr15161
      Expr1014916
      Expr1038059
      Expr1151844
      Expr2004013
      Expr2022235
    Drives_construct: WBCnstr00026318
    Construct_product: WBCnstr00026318
    Microarray_results (18)
    Expression_cluster (129)
    Interaction (15)
  Map_info: Map: X Position: -14.3903
    Positive: Positive_clone: F52H2 Inferred_automatically: From sequence, transcript, pseudogene data
    Pseudo_map_position
  Reference: WBPaper00038491
    WBPaper00042257
    WBPaper00055090
  Remark: Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. CGC_data_submission
  Method: Gene