WormBase Tree Display for Gene: WBGene00018604
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WBGene00018604 | SMap | S_parent | Sequence | F48E3 | |||||
---|---|---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||||
Name | CGC_name | uggt-1 | Paper_evidence | WBPaper00040397 | |||||
Person_evidence | WBPerson12962 | ||||||||
Sequence_name | F48E3.3 | ||||||||
Molecular_name | F48E3.3 | ||||||||
F48E3.3.1 | |||||||||
CE02751 | |||||||||
Other_name | CELE_F48E3.3 | Accession_evidence | NDB | BX284606 | |||||
Public_name | uggt-1 | ||||||||
DB_info | Database | AceView | gene | XI114 | |||||
WormQTL | gene | WBGene00018604 | |||||||
WormFlux | gene | WBGene00018604 | |||||||
NDB | locus_tag | CELE_F48E3.3 | |||||||
Panther | gene | CAEEL|WormBase=WBGene00018604|UniProtKB=Q9GPA0 | |||||||
family | PTHR11226 | ||||||||
NCBI | gene | 181007 | |||||||
RefSeq | protein | NM_076867.5 | |||||||
TREEFAM | TREEFAM_ID | TF300320 | |||||||
TrEMBL | UniProtAcc | Q9GPA0 | |||||||
UniProt_GCRP | UniProtAcc | Q9GPA0 | |||||||
Species | Caenorhabditis elegans | ||||||||
History | Version_change | 1 | 28 May 2004 13:31:00 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
2 | 11 Nov 2011 16:17:07 | WBPerson2970 | Name_change | CGC_name | uggt-1 | ||||
Status | Live | ||||||||
Gene_info | Biotype | SO:0001217 | |||||||
Gene_class | uggt | ||||||||
Allele (89) | |||||||||
Strain | WBStrain00002539 | ||||||||
RNASeq_FPKM (74) | |||||||||
GO_annotation (22) | |||||||||
Ortholog (42) | |||||||||
Paralog | WBGene00009178 | Caenorhabditis elegans | From_analysis | TreeFam | |||||
Panther | |||||||||
WormBase-Compara | |||||||||
Structured_description | Concise_description | uggt-1 encodes one of two C. elegans homologs of UDP-Glc:glycoprotein glucosyltransferase (UGGT), an endoplasmic reticulum enzyme involved in quality control of glycoprotein folding; expression of uggt-1 in S. pombe cells lacking functional UGGT activity indicates that UGGT-1 displays UDP-Glc:glycoprotein glucosyltransferase activity; loss of uggt-1 activity via RNAi results in larval developmental delay and a shortened lifespan; uggt-1 is expressed throughout larval development, with peak levels seen at the L2/L3 stages, and uggt-1 expression is upregulated in an ire-1-dependent manner in response to endoplasmic reticulum stress; a uggt-1::gfp promoter fusion is expressed in the nervous system, including the amphid and phasmid neurons, the nerve ring, and the dorsal and ventral nerve cords. | Paper_evidence | WBPaper00040397 | |||||
Curator_confirmed | WBPerson1843 | ||||||||
Date_last_updated | 14 Nov 2011 00:00:00 | ||||||||
Automated_description | Enables UDP-glucose:glycoprotein glucosyltransferase activity. Involved in IRE1-mediated unfolded protein response; protein N-linked glycosylation via asparagine; and regulation of nematode larval development. Predicted to be located in endoplasmic reticulum. Expressed in several structures, including anal depressor muscle; germ line; neurons; pharyngeal-intestinal valve; and rectal gland cell. Is an ortholog of human UGGT1 (UDP-glucose glycoprotein glucosyltransferase 1) and UGGT2 (UDP-glucose glycoprotein glucosyltransferase 2). | Paper_evidence | WBPaper00065943 | ||||||
Curator_confirmed | WBPerson324 | ||||||||
WBPerson37462 | |||||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
Molecular_info | Corresponding_CDS | F48E3.3 | |||||||
Corresponding_transcript | F48E3.3.1 | ||||||||
Other_sequence (62) | |||||||||
Associated_feature | WBsf654142 | ||||||||
WBsf670729 | |||||||||
WBsf670730 | |||||||||
WBsf237582 | |||||||||
Experimental_info | RNAi_result (14) | ||||||||
Expr_pattern (14) | |||||||||
Drives_construct | WBCnstr00003112 | ||||||||
WBCnstr00004548 | |||||||||
WBCnstr00014223 | |||||||||
WBCnstr00026387 | |||||||||
WBCnstr00041864 | |||||||||
Construct_product | WBCnstr00026387 | ||||||||
Microarray_results (20) | |||||||||
Expression_cluster (171) | |||||||||
Interaction (81) | |||||||||
Map_info | Map | X | Position | -1.66215 | |||||
Positive | Positive_clone | F48E3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
Pseudo_map_position | |||||||||
Reference | WBPaper00029024 | ||||||||
WBPaper00031857 | |||||||||
WBPaper00033099 | |||||||||
WBPaper00038491 | |||||||||
WBPaper00039794 | |||||||||
WBPaper00040397 | |||||||||
WBPaper00042697 | |||||||||
WBPaper00055090 | |||||||||
WBPaper00060116 | |||||||||
WBPaper00060970 | |||||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
Method | Gene |