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WormBase Tree Display for Gene: WBGene00018491

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Name Class

WBGene00018491SMapS_parentSequenceF46E10
IdentityVersion2
NameCGC_namemdh-1Person_evidenceWBPerson676
Sequence_nameF46E10.10
Molecular_nameF46E10.10
F46E10.10.1
CE20820
Other_nameF46E10.gCurator_confirmedWBPerson1983
RemarkOld cosmid naming mapped via unique overlapping PCR_product on CDSs
CELE_F46E10.10Accession_evidenceNDBBX284605
Public_namemdh-1
DB_infoDatabase (12)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:31:00WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
218 Aug 2010 11:15:35WBPerson2970Name_changeCGC_namemdh-1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classmdh
Allele (26)
RNASeq_FPKM (74)
GO_annotation (20)
Contained_in_operonCEOP5120
Ortholog (42)
Structured_descriptionConcise_descriptionmdh-1 encodes a malate dehydrogenase; by homology, MDH-1 is predicted to function to reversibly catalyze the formation of oxaloacetate from malate.Curator_confirmedWBPerson1843
Date_last_updated26 Oct 2011 00:00:00
Automated_descriptionEnables L-malate dehydrogenase activity. Involved in malate metabolic process. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 88. Is an ortholog of human MDH1 (malate dehydrogenase 1).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:0112222Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:6970)
Molecular_infoCorresponding_CDSF46E10.10
Corresponding_CDS_historyF46E10.10b:wp275
F46E10.10c:wp275
Corresponding_transcriptF46E10.10.1
Other_sequence (374)
Associated_featureWBsf655562
WBsf669059
WBsf981954
WBsf1000291
WBsf1000292
WBsf233819
WBsf233820
WBsf233821
WBsf233822
Experimental_infoRNAi_resultWBRNAi00015088Inferred_automaticallyRNAi_primary
WBRNAi00106994Inferred_automaticallyRNAi_primary
WBRNAi00047523Inferred_automaticallyRNAi_primary
WBRNAi00033295Inferred_automaticallyRNAi_primary
WBRNAi00088638Inferred_automaticallyRNAi_primary
WBRNAi00103124Inferred_automaticallyRNAi_primary
WBRNAi00088745Inferred_automaticallyRNAi_primary
WBRNAi00103123Inferred_automaticallyRNAi_primary
Expr_patternExpr12927
Expr1023310
Expr1037971
Expr1151361
Expr2013465
Expr2031699
Drives_constructWBCnstr00026475
Construct_productWBCnstr00026475
Microarray_results (29)
Expression_cluster (170)
Interaction (52)
WBProcessWBbiopr:00000096
Map_infoMapVPosition0.000662
PositivePositive_cloneF46E10Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (15)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene