WormBase Tree Display for Gene: WBGene00018467
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| WBGene00018467 | SMap | S_parent | Sequence | F45E1 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | sdpn-1 | Person_evidence | WBPerson217 | |||||
| Sequence_name | F45E1.7 | ||||||||
| Molecular_name | F45E1.7a | ||||||||
| F45E1.7a.1 | |||||||||
| CE29323 | |||||||||
| F45E1.7b | |||||||||
| CE37111 | |||||||||
| F45E1.7a.2 | |||||||||
| F45E1.7b.1 | |||||||||
| Other_name | CELE_F45E1.7 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | sdpn-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:31:00 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 02 Aug 2006 11:39:27 | WBPerson2970 | Name_change | CGC_name | sdpn-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | sdpn | ||||||||
| Allele (194) | |||||||||
| Strain | WBStrain00032158 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (12) | |||||||||
| Ortholog (46) | |||||||||
| Paralog | WBGene00018974 | Caenorhabditis elegans | From_analysis | Panther | |||||
| Structured_description | Concise_description | sdpn-1 encodes the C. elegans syndapin ortholog; an SDPN-1::GFP fusion protein is highly expressed in the intestine, where it localizes to basolateral recycling endosomes; SDPN-1 localization to basolateral recycling endosomes is dependent upon ALX-1, one of two C. elegans Bro1 domain-containing proteins, and RME-1. | Paper_evidence | WBPaper00031193 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 23 Jun 2008 00:00:00 | ||||||||
| Automated_description | Predicted to enable phospholipid binding activity. Involved in endocytic recycling. Located in early endosome and recycling endosome membrane. Expressed in intestine; pharyngeal muscle cell; and pharynx. Used to study Huntington's disease. Is an ortholog of human PACSIN1 (protein kinase C and casein kinase substrate in neurons 1); PACSIN2 (protein kinase C and casein kinase substrate in neurons 2); and PACSIN3 (protein kinase C and casein kinase substrate in neurons 3). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Experimental_model | DOID:1289 | Homo sapiens | Paper_evidence | WBPaper00064224 | ||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 09 Aug 2022 00:00:00 | ||||||||
| DOID:12858 | Homo sapiens | Paper_evidence | WBPaper00050114 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 15 Mar 2023 00:00:00 | ||||||||
| Models_disease_asserted | WBDOannot00001315 | ||||||||
| WBDOannot00001316 | |||||||||
| Molecular_info | Corresponding_CDS | F45E1.7a | |||||||
| F45E1.7b | |||||||||
| Corresponding_CDS_history | F45E1.7:wp128 | ||||||||
| Corresponding_transcript | F45E1.7a.1 | ||||||||
| F45E1.7a.2 | |||||||||
| F45E1.7b.1 | |||||||||
| Other_sequence (13) | |||||||||
| Associated_feature (22) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00033484 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00001598 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00065624 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00015015 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00047390 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr152 | ||||||||
| Expr13136 | |||||||||
| Expr1022715 | |||||||||
| Expr1037958 | |||||||||
| Expr1151238 | |||||||||
| Expr2015667 | |||||||||
| Expr2033900 | |||||||||
| Drives_construct | WBCnstr00001783 | ||||||||
| WBCnstr00005954 | |||||||||
| WBCnstr00026495 | |||||||||
| WBCnstr00038586 | |||||||||
| Construct_product | WBCnstr00001783 | ||||||||
| WBCnstr00005953 | |||||||||
| WBCnstr00005954 | |||||||||
| WBCnstr00026495 | |||||||||
| WBCnstr00038586 | |||||||||
| Microarray_results (24) | |||||||||
| Expression_cluster (129) | |||||||||
| Interaction (50) | |||||||||
| Map_info | Map | X | Position | -0.73688 | Error | 0.012044 | |||
| Positive | Positive_clone | F45E1 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (15) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
