WormBase Tree Display for Gene: WBGene00017241
expand all nodes | collapse all nodes | view schema
WBGene00017241 | SMap | S_parent | Sequence | F08C6 | |||
---|---|---|---|---|---|---|---|
Identity | Version | 2 | |||||
Name | CGC_name | pcyt-1 | Person_evidence | WBPerson1711 | |||
Sequence_name | F08C6.2 | ||||||
Molecular_name (6) | |||||||
Other_name | CELE_F08C6.2 | Accession_evidence | NDB | BX284606 | |||
Public_name | pcyt-1 | ||||||
DB_info | Database (14) | ||||||
Species | Caenorhabditis elegans | ||||||
History | Version_change (2) | ||||||
Status | Live | ||||||
Gene_info | Biotype | SO:0001217 | |||||
Gene_class | pcyt | ||||||
Allele (156) | |||||||
Strain | WBStrain00031168 | ||||||
WBStrain00037474 | |||||||
RNASeq_FPKM (74) | |||||||
GO_annotation (15) | |||||||
Ortholog (42) | |||||||
Paralog | WBGene00017878 | Caenorhabditis elegans | From_analysis | TreeFam | |||
WBGene00021215 | Caenorhabditis elegans | From_analysis | Panther | ||||
WormBase-Compara | |||||||
WBGene00016531 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
WBGene00021352 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||
Structured_description | Concise_description | pcyt-1 encodes a lipid-activated CTP:phosphocholine cytidylyltransferase (CCT), with CCT activity in vitro; recombinant PCYT-1 is most activated by a 1:1 mixture of phosphatidylcholine:oleate vesicles; an inhibitory 21-residue segment (residues 246-266) is critical for specific activation of PCYT-1 by lipids, since deletion or mutation of this segment causes PCYT-1 to be constitutively active without its normal lipid substrate. | Paper_evidence | WBPaper00004651 | |||
WBPaper00004877 | |||||||
WBPaper00005654 | |||||||
WBPaper00035321 | |||||||
Curator_confirmed | WBPerson1843 | ||||||
WBPerson567 | |||||||
Date_last_updated | 14 Oct 2011 00:00:00 | ||||||
Automated_description | Enables choline-phosphate cytidylyltransferase activity. Involved in phosphatidylcholine biosynthetic process. Expressed in head. Human ortholog(s) of this gene implicated in spondylometaphyseal dysplasia with cone-rod dystrophy. Is an ortholog of human PCYT1A (phosphate cytidylyltransferase 1A, choline) and PCYT1B (phosphate cytidylyltransferase 1B, choline). | Paper_evidence | WBPaper00065943 | ||||
Curator_confirmed | WBPerson324 | ||||||
WBPerson37462 | |||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||
Date_last_updated | 29 Nov 2023 00:00:00 | ||||||
Disease_info | Potential_model | DOID:0112300 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8754) | ||
Molecular_info | Corresponding_CDS | F08C6.2a | |||||
F08C6.2b | |||||||
Corresponding_CDS_history | F08C6.2:wp149 | ||||||
Corresponding_transcript | F08C6.2a.1 | ||||||
F08C6.2b.1 | |||||||
Other_sequence (77) | |||||||
Associated_feature (20) | |||||||
Experimental_info | RNAi_result (34) | ||||||
Expr_pattern | Chronogram1664 | ||||||
Expr5678 | |||||||
Expr1019705 | |||||||
Expr1037403 | |||||||
Expr1147952 | |||||||
Expr2014791 | |||||||
Expr2033025 | |||||||
Drives_construct | WBCnstr00002991 | ||||||
WBCnstr00027460 | |||||||
Construct_product | WBCnstr00027460 | ||||||
Microarray_results (25) | |||||||
Expression_cluster (177) | |||||||
Interaction (73) | |||||||
Map_info | Map | X | Position | -1.49196 | |||
Positive | Positive_clone | F08C6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||
Pseudo_map_position | |||||||
Reference (16) | |||||||
Picture | WBPicture0000013096 | ||||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||
Method | Gene |