WormBase Tree Display for Gene: WBGene00017241
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WBGene00017241 | SMap | S_parent | Sequence | F08C6 | ||
---|---|---|---|---|---|---|
Identity (6) | ||||||
Gene_info | Biotype | SO:0001217 | ||||
Gene_class | pcyt | |||||
Allele (156) | ||||||
Strain | WBStrain00031168 | |||||
WBStrain00037474 | ||||||
RNASeq_FPKM (74) | ||||||
GO_annotation (15) | ||||||
Ortholog (42) | ||||||
Paralog | WBGene00017878 | Caenorhabditis elegans | From_analysis | TreeFam | ||
WBGene00021215 | Caenorhabditis elegans | From_analysis | Panther | |||
WormBase-Compara | ||||||
WBGene00016531 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
WBGene00021352 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||
Structured_description | Concise_description | pcyt-1 encodes a lipid-activated CTP:phosphocholine cytidylyltransferase (CCT), with CCT activity in vitro; recombinant PCYT-1 is most activated by a 1:1 mixture of phosphatidylcholine:oleate vesicles; an inhibitory 21-residue segment (residues 246-266) is critical for specific activation of PCYT-1 by lipids, since deletion or mutation of this segment causes PCYT-1 to be constitutively active without its normal lipid substrate. | Paper_evidence | WBPaper00004651 | ||
WBPaper00004877 | ||||||
WBPaper00005654 | ||||||
WBPaper00035321 | ||||||
Curator_confirmed | WBPerson1843 | |||||
WBPerson567 | ||||||
Date_last_updated | 14 Oct 2011 00:00:00 | |||||
Automated_description | Enables choline-phosphate cytidylyltransferase activity. Involved in phosphatidylcholine biosynthetic process. Expressed in head. Human ortholog(s) of this gene implicated in spondylometaphyseal dysplasia with cone-rod dystrophy. Is an ortholog of human PCYT1A (phosphate cytidylyltransferase 1A, choline) and PCYT1B (phosphate cytidylyltransferase 1B, choline). | Paper_evidence | WBPaper00065943 | |||
Curator_confirmed | WBPerson324 | |||||
WBPerson37462 | ||||||
Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | |||||
Date_last_updated | 29 Nov 2023 00:00:00 | |||||
Disease_info | Potential_model | DOID:0112300 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:8754) | |
Molecular_info | Corresponding_CDS | F08C6.2a | ||||
F08C6.2b | ||||||
Corresponding_CDS_history | F08C6.2:wp149 | |||||
Corresponding_transcript | F08C6.2a.1 | |||||
F08C6.2b.1 | ||||||
Other_sequence (77) | ||||||
Associated_feature (20) | ||||||
Experimental_info | RNAi_result (34) | |||||
Expr_pattern | Chronogram1664 | |||||
Expr5678 | ||||||
Expr1019705 | ||||||
Expr1037403 | ||||||
Expr1147952 | ||||||
Expr2014791 | ||||||
Expr2033025 | ||||||
Drives_construct | WBCnstr00002991 | |||||
WBCnstr00027460 | ||||||
Construct_product | WBCnstr00027460 | |||||
Microarray_results (25) | ||||||
Expression_cluster (177) | ||||||
Interaction (73) | ||||||
Map_info | Map | X | Position | -1.49196 | ||
Positive | Positive_clone | F08C6 | Inferred_automatically | From sequence, transcript, pseudogene data | ||
Pseudo_map_position | ||||||
Reference (16) | ||||||
Picture | WBPicture0000013096 | |||||
Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||
Method | Gene |