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WormBase Tree Display for Gene: WBGene00017121

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Name Class

WBGene00017121SMapS_parentSequenceE04A4
IdentityVersion2
NameCGC_namecyc-2.1Person_evidenceWBPerson338
Sequence_nameE04A4.7
Molecular_nameE04A4.7
E04A4.7.1
CE16968
E04A4.7.2
Other_nameCELE_E04A4.7Accession_evidenceNDBBX284604
Public_namecyc-2.1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change128 May 2004 13:30:58WBPerson1971EventImportedInitial conversion from CDS class of stlace from WS125
209 Mar 2007 14:55:52WBPerson2970Name_changeCGC_namecyc-2.1
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classcyc
Allele (24)
RNASeq_FPKM (74)
GO_annotation (13)
Contained_in_operonCEOP4148
Ortholog (41)
ParalogWBGene00013854Caenorhabditis elegansFrom_analysisPanther
WormBase-Compara
Structured_descriptionConcise_descriptioncyc-2.1 encodes, along with cyc-2.2, one of two C. elegans cytochrome c proteins; the product of cyc-2.1 is predicted to function in the electron transport chain by transferring electrons from respiratory chain Complex III to Complex IV; large-scale RNAi screens indicate the cyc-2.1 activity is required for embryonic and larval development as well as for normal brood sizes and growth rates.Paper_evidenceWBPaper00001363
WBPaper00005654
WBPaper00006395
WBPaper00024497
WBPaper00025054
WBPaper00041884
Curator_confirmedWBPerson1843
Date_last_updated25 Mar 2013 00:00:00
Automated_descriptionEnables electron transfer activity. Involved in electron transport chain. Predicted to be located in mitochondrial intermembrane space. Expressed in body wall musculature; excretory cell; intestinal cell; nervous system; and pharynx. Human ortholog(s) of this gene implicated in several diseases, including Huntington's disease; carcinoma (multiple); and thrombocytopenia. Is an ortholog of human CYCS (cytochrome c, somatic).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Disease_infoPotential_modelDOID:4947Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:19986)
DOID:1588Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:19986)
DOID:3908Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:19986)
DOID:12858Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:19986)
DOID:1793Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:19986)
DOID:3907Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:19986)
Molecular_infoCorresponding_CDSE04A4.7
Corresponding_transcriptE04A4.7.1
E04A4.7.2
Other_sequence (219)
Associated_featureWBsf651775
WBsf667905
WBsf667906
WBsf981752
WBsf996386
WBsf230008
Experimental_infoRNAi_result (24)
Expr_patternExpr11086
Expr1017653
Expr1037354
Expr1147651
Expr2010651
Expr2028891
Drives_constructWBCnstr00018157
WBCnstr00027556
Construct_productWBCnstr00027556
Microarray_results (30)
Expression_cluster (131)
Interaction (188)
Map_infoMapIVPosition0.778341Error0.012862
PositivePositive_cloneE04A4Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
ReferenceWBPaper00001363
WBPaper00038491
WBPaper00041884
WBPaper00049828
WBPaper00055090
WBPaper00057083
WBPaper00063976
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene