WormBase Tree Display for Gene: WBGene00017084
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| WBGene00017084 | SMap | S_parent | Sequence | E01A2 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | Sequence_name | E01A2.1 | |||||||
| Molecular_name | E01A2.1a | ||||||||
| E01A2.1a.1 | |||||||||
| CE24869 | |||||||||
| E01A2.1b | |||||||||
| CE41889 | |||||||||
| E01A2.1a.2 | |||||||||
| E01A2.1b.1 | |||||||||
| Other_name | CELE_E01A2.1 | Accession_evidence | NDB | BX284601 | |||||
| Public_name | E01A2.1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:58 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Allele (44) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00005447 | ||||||||
| 00005448 | |||||||||
| 00005449 | |||||||||
| 00005450 | |||||||||
| 00005451 | |||||||||
| 00091005 | |||||||||
| 00122566 | |||||||||
| 00122567 | |||||||||
| Ortholog (34) | |||||||||
| Structured_description | Concise_description | E01A2.1 encodes a glutamate cysteine ligase regulatory subunit; by homology, the product of E01A2.1, along with the catalytic subunit GCS-1 (gamma-glutamylcysteine synthetase), is predicted to participate in the rate-limiting first step of glutathione (GSH) synthesis. | Paper_evidence | WBPaper00045711 | |||||
| WBPaper00036390 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 10 Dec 2014 00:00:00 | ||||||||
| Automated_description | Predicted to enable enzyme regulator activity. Predicted to be involved in glutathione biosynthetic process. Predicted to be part of glutamate-cysteine ligase complex. Human ortholog(s) of this gene implicated in myocardial infarction and vascular dementia. Is an ortholog of human GCLM (glutamate-cysteine ligase modifier subunit). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:8725 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4312) | ||||
| DOID:5844 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:4312) | ||||||
| Molecular_info | Corresponding_CDS | E01A2.1a | |||||||
| E01A2.1b | |||||||||
| Corresponding_CDS_history | E01A2.1:wp185 | ||||||||
| Corresponding_transcript | E01A2.1a.1 | ||||||||
| E01A2.1a.2 | |||||||||
| E01A2.1b.1 | |||||||||
| Other_sequence | CRC05029_1 | ||||||||
| PPC02616_1 | |||||||||
| CBC02469_1 | |||||||||
| Hbac_isotig02772 | |||||||||
| EX910666.1 | |||||||||
| PP01574 | |||||||||
| HBC19200_1 | |||||||||
| Associated_feature (13) | |||||||||
| Experimental_info | RNAi_result (16) | ||||||||
| Expr_pattern | Expr1013773 | ||||||||
| Expr1037343 | |||||||||
| Expr1147548 | |||||||||
| Expr2002111 | |||||||||
| Expr2020336 | |||||||||
| Drives_construct | WBCnstr00027581 | ||||||||
| Construct_product | WBCnstr00027581 | ||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (117) | |||||||||
| Interaction (25) | |||||||||
| Map_info | Positive | Positive_clone | E01A2 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||
| Interpolated_map_position | I | -1.69975 | |||||||
| Reference | WBPaper00038491 | ||||||||
| WBPaper00045711 | |||||||||
| WBPaper00055090 | |||||||||
| Method | Gene |
