WormBase Tree Display for Gene: WBGene00017012
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| WBGene00017012 | SMap | S_parent | Sequence | D1009 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | acs-22 | Person_evidence | WBPerson237 | |||||
| WBPerson9275 | |||||||||
| Sequence_name | D1009.1 | ||||||||
| Molecular_name | D1009.1a | ||||||||
| D1009.1a.1 | |||||||||
| CE04285 | |||||||||
| D1009.1c | |||||||||
| CE51329 | |||||||||
| D1009.1d | |||||||||
| CE51246 | |||||||||
| D1009.1c.1 | |||||||||
| D1009.1d.1 | |||||||||
| Other_name | CELE_D1009.1 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | acs-22 | ||||||||
| DB_info | Database | AceView | gene | XJ557 | |||||
| WormQTL | gene | WBGene00017012 | |||||||
| WormFlux | gene | WBGene00017012 | |||||||
| NDB | locus_tag | CELE_D1009.1 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00017012|UniProtKB=Q18916 | |||||||
| family | PTHR43107 | ||||||||
| NCBI | gene | 181138 | |||||||
| RefSeq | protein | NM_001392815.1 | |||||||
| NM_001322629.4 | |||||||||
| NM_077108.6 | |||||||||
| TrEMBL | UniProtAcc | Q18916 | |||||||
| A0A131MBB2 | |||||||||
| A0A131MB92 | |||||||||
| UniProt_GCRP | UniProtAcc | Q18916 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:58 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 13 Mar 2009 14:10:25 | WBPerson9133 | Name_change | CGC_name | acs-22 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | acs | ||||||||
| Allele (144) | |||||||||
| Strain | WBStrain00004763 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00001951 | ||||||||
| 00001952 | |||||||||
| 00001953 | |||||||||
| 00001954 | |||||||||
| 00001955 | |||||||||
| 00001956 | |||||||||
| 00001957 | |||||||||
| 00062816 | |||||||||
| Ortholog (44) | |||||||||
| Paralog (17) | |||||||||
| Structured_description | Concise_description | acs-22 encodes a protein homologous to the mammalian FATP1 and FATP4 fatty acid transport proteins (FATP)/very long chain fatty acid acyl-CoA synthetases; acs-22 functions redundantly with acs-20 to regulate formation of the cuticle surface barrier that prevents penetration of small molecules; acs-22 may affect cuticle development via its role in incorporation of very long chain fatty acids, but not other fatty acids, into sphingomyelin; an acs-22::gfp promoter fusion is expressed strongly in the intestine, with weaker expression seen in the pharynx, head neurons, and hypodermis. | Paper_evidence | WBPaper00035868 | |||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 03 Feb 2010 00:00:00 | ||||||||
| Automated_description | Predicted to enable long-chain fatty acid transporter activity and long-chain fatty acid-CoA ligase activity. Predicted to be involved in triglyceride homeostasis. Located in endoplasmic reticulum. Expressed in head neurons; hypodermis; and pharynx. Human ortholog(s) of this gene implicated in obesity. Is an ortholog of human SLC27A1 (solute carrier family 27 member 1) and SLC27A4 (solute carrier family 27 member 4). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:9970 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10998) | ||||
| Molecular_info | Corresponding_CDS | D1009.1a | |||||||
| D1009.1c | |||||||||
| D1009.1d | |||||||||
| Corresponding_CDS_history | D1009.1b:wp271 | ||||||||
| Corresponding_transcript | D1009.1a.1 | ||||||||
| D1009.1c.1 | |||||||||
| D1009.1d.1 | |||||||||
| Other_sequence (52) | |||||||||
| Associated_feature (16) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00043335 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00012490 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00030314 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00092595 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr8894 | ||||||||
| Expr1020922 | |||||||||
| Expr1037310 | |||||||||
| Expr1147315 | |||||||||
| Expr2009212 | |||||||||
| Expr2027449 | |||||||||
| Drives_construct | WBCnstr00013588 | ||||||||
| WBCnstr00022751 | |||||||||
| WBCnstr00027639 | |||||||||
| Construct_product | WBCnstr00014925 | ||||||||
| WBCnstr00022756 | |||||||||
| WBCnstr00027639 | |||||||||
| Microarray_results (28) | |||||||||
| Expression_cluster (202) | |||||||||
| Interaction (87) | |||||||||
| Map_info | Map | X | Position | 0.449566 | Error | 0.000197 | |||
| Positive | Positive_clone | D1009 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference (15) | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
