WormBase Tree Display for Gene: WBGene00015813
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| WBGene00015813 | SMap | S_parent | Sequence | C16A3 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 3 | |||||||
| Name | CGC_name | thoc-2 | Person_evidence | WBPerson4055 | |||||
| Sequence_name | C16A3.8 | ||||||||
| Molecular_name | C16A3.8 | ||||||||
| C16A3.8.1 | |||||||||
| CE47895 | |||||||||
| Other_name | tag-213 | ||||||||
| CELE_C16A3.8 | Accession_evidence | NDB | BX284603 | ||||||
| Public_name | thoc-2 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:56 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 22 Dec 2004 16:59:41 | WBPerson2970 | Name_change | CGC_name | tag-213 | ||||
| 3 | 20 Jul 2007 11:50:19 | WBPerson2970 | Name_change | CGC_name | thoc-2 | ||||
| Other_name | tag-213 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | thoc | ||||||||
| Allele (73) | |||||||||
| Strain | WBStrain00035968 | ||||||||
| WBStrain00007859 | |||||||||
| WBStrain00007860 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00060013 | ||||||||
| 00060014 | |||||||||
| 00060015 | |||||||||
| 00060016 | |||||||||
| 00060017 | |||||||||
| 00060018 | |||||||||
| 00121591 | |||||||||
| 00121592 | |||||||||
| 00121593 | |||||||||
| Contained_in_operon | CEOP3856 | ||||||||
| Ortholog (48) | |||||||||
| Structured_description | Concise_description | thoc-2 encodes the C. elegans ortholog of mammalian THOC2 and S. cerevisiae Tho2, conserved subunits of the THO complex involved in mRNP biogenesis as part of transcription elongation, mRNA maturation, and export; in C. elegans, thoc-2 activity is required for progression through the meiotic and mitotic cell cycles and thus for normal fertility and organismal development. | Paper_evidence | WBPaper00041879 | |||||
| WBPaper00041588 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| Date_last_updated | 09 Jan 2013 00:00:00 | ||||||||
| Automated_description | Predicted to enable mRNA binding activity. Predicted to be involved in mRNA export from nucleus. Predicted to be located in nucleus. Predicted to be part of THO complex part of transcription export complex. Human ortholog(s) of this gene implicated in X-linked intellectual disability-short stature-overweight syndrome. Is an ortholog of human THOC2 (THO complex subunit 2). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Potential_model | DOID:0112056 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:19073) | ||||
| Molecular_info | Corresponding_CDS | C16A3.8 | |||||||
| Corresponding_transcript | C16A3.8.1 | ||||||||
| Other_sequence (18) | |||||||||
| Associated_feature | WBsf645262 | ||||||||
| WBsf659065 | |||||||||
| WBsf659066 | |||||||||
| WBsf659067 | |||||||||
| WBsf659068 | |||||||||
| WBsf225088 | |||||||||
| WBsf225089 | |||||||||
| Experimental_info | RNAi_result (17) | ||||||||
| Expr_pattern | Expr13874 | ||||||||
| Expr1014929 | |||||||||
| Expr1036770 | |||||||||
| Expr1144713 | |||||||||
| Expr2017390 | |||||||||
| Expr2035529 | |||||||||
| Drives_construct | WBCnstr00028546 | ||||||||
| Construct_product | WBCnstr00028546 | ||||||||
| WBCnstr00040171 | |||||||||
| Microarray_results (21) | |||||||||
| Expression_cluster (115) | |||||||||
| Interaction (52) | |||||||||
| Map_info | Map | III | Position | -1.3546 | Error | 0.007276 | |||
| Positive | Positive_clone | C16A3 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 4991 | |||||||
| 5627 | |||||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00027412 | ||||||||
| WBPaper00038491 | |||||||||
| WBPaper00041209 | |||||||||
| WBPaper00041588 | |||||||||
| WBPaper00041879 | |||||||||
| WBPaper00043900 | |||||||||
| WBPaper00044440 | |||||||||
| WBPaper00044806 | |||||||||
| WBPaper00052341 | |||||||||
| WBPaper00055090 | |||||||||
| Picture | WBPicture0000013093 | ||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
