WormBase Tree Display for Gene: WBGene00015565

WBGene00015565 SMap: S_parent: Sequence: C07D8
  Identity: Version: 1
    Name: Sequence_name: C07D8.6
      Molecular_name: C07D8.6
        C07D8.6.1
        CE06776
      Other_name: CELE_C07D8.6 Accession_evidence: NDB BX284606
      Public_name: C07D8.6
    DB_info: Database: AceView gene XH961
        WormQTL gene WBGene00015565
        WormFlux gene WBGene00015565
        NDB locus_tag CELE_C07D8.6
        Panther gene CAEEL|WormBase=WBGene00015565|UniProtKB=P91020
          family PTHR11732
        NCBI gene 180997
        RefSeq protein NM_076841.8
        TrEMBL UniProtAcc P91020
        UniProt_GCRP UniProtAcc P91020
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:56 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (35)
    RNASeq_FPKM (74)
    GO_annotation: 00049800
      00049801
      00121435
    Ortholog (72)
    Paralog (13)
    Structured_description: Automated_description: Predicted to enable alditol:NADP+ 1-oxidoreductase activity. Predicted to be located in cytosol. Expressed in germ line. Human ortholog(s) of this gene implicated in several diseases, including diabetic neuropathy; gastrointestinal system cancer (multiple); and type 2 diabetes mellitus. Is an ortholog of human AKR1B1 (aldo-keto reductase family 1 member B); AKR1B10 (aldo-keto reductase family 1 member B10); and AKR1B15 (aldo-keto reductase family 1 member B15). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:9352 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:381)
      DOID:2349 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:381)
      DOID:10534 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:381)
      DOID:8947 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:381)
      DOID:684 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:381)
      DOID:9743 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:381)
      DOID:83 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:381)
  Molecular_info: Corresponding_CDS: C07D8.6
    Corresponding_transcript: C07D8.6.1
    Other_sequence (101)
    Associated_feature: WBsf235923
  Experimental_info: RNAi_result: WBRNAi00092615 Inferred_automatically: RNAi_primary
      WBRNAi00010387 Inferred_automatically: RNAi_primary
      WBRNAi00039997 Inferred_automatically: RNAi_primary
      WBRNAi00061370 Inferred_automatically: RNAi_primary
      WBRNAi00028628 Inferred_automatically: RNAi_primary
      WBRNAi00007927 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr4146
      Expr1018843
      Expr1036666
      Expr1144075
      Expr2000572
      Expr2018798
    Drives_construct: WBCnstr00028747
    Construct_product: WBCnstr00028747
    Microarray_results (20)
    Expression_cluster (199)
    Interaction (55)
  Map_info: Positive: Positive_clone: C07D8 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: X -1.75248
  Reference: WBPaper00028360
    WBPaper00028527
    WBPaper00029197
    WBPaper00038491
    WBPaper00055090
  Method: Gene