WormBase Tree Display for Gene: WBGene00015565

WBGene00015565 SMap: S_parent: Sequence: C07D8
  Identity: Version: 1
    Name: Sequence_name: C07D8.6
      Molecular_name: C07D8.6
        C07D8.6.1
        CE06776
      Other_name: CELE_C07D8.6 Accession_evidence: NDB BX284606
      Public_name: C07D8.6
    DB_info: Database: AceView gene XH961
        WormQTL gene WBGene00015565
        WormFlux gene WBGene00015565
        NDB locus_tag CELE_C07D8.6
        Panther gene CAEEL|WormBase=WBGene00015565|UniProtKB=P91020
          family PTHR11732
        NCBI gene 180997
        RefSeq protein NM_076841.8
        TrEMBL UniProtAcc P91020
        UniProt_GCRP UniProtAcc P91020
    Species: Caenorhabditis elegans
    History: Version_change: 1 28 May 2004 13:30:56 WBPerson1971 Event: Imported: Initial conversion from CDS class of stlace from WS125
    Status: Live
  Gene_info: Biotype: SO:0001217
    Allele (35)
    RNASeq_FPKM (74)
    GO_annotation: 00049800
      00049801
      00121435
    Ortholog: WBGene00051346 Caenorhabditis remanei From_analysis: OMA
            TreeFam
            Inparanoid_8
            WormBase-Compara
      WBGene00032231 Caenorhabditis briggsae From_analysis: OrthoMCL
            OMA
            Inparanoid_8
            WormBase-Compara
      WBGene00139978 Caenorhabditis brenneri From_analysis: OMA
            Inparanoid_8
      WBGene00132626 Caenorhabditis japonica From_analysis: OMA
            TreeFam
            Inparanoid_8
      WBGene00136933 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
      WBGene00142293 Caenorhabditis brenneri From_analysis: OMA
      WBGene00157652 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
      WBGene00162440 Caenorhabditis brenneri From_analysis: OMA
            TreeFam
      WBGene00136557 Caenorhabditis japonica From_analysis: TreeFam
            Inparanoid_8
      WBGene00106950 Pristionchus pacificus From_analysis: OMA
      WBGene00222303 Brugia malayi From_analysis: WormBase-Compara
      CBOVI.g2592 Caenorhabditis bovis From_analysis: WormBase-Compara
      CBOVI.g2593 Caenorhabditis bovis From_analysis: WormBase-Compara
      CBOVI.g2880 Caenorhabditis bovis From_analysis: WormBase-Compara
      CSP21.g1598 Caenorhabditis parvicauda From_analysis: WormBase-Compara
      CSP26.g19405 Caenorhabditis zanzibari From_analysis: WormBase-Compara
      CSP31.g14047 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP31.g16788 Caenorhabditis uteleia From_analysis: WormBase-Compara
      CSP38.g17273 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP38.g17274 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP38.g17276 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP38.g17277 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP38.g17278 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP38.g17279 Caenorhabditis quiockensis From_analysis: WormBase-Compara
      CSP40.g21257 Caenorhabditis tribulationis From_analysis: WormBase-Compara
      Cang_2012_03_13_00713.g13630 Caenorhabditis angaria From_analysis: WormBase-Compara
      Cnig_chr_X.g24732 Caenorhabditis nigoni From_analysis: WormBase-Compara
      Csp11.Scaffold629.g12484 Caenorhabditis tropicalis From_analysis: WormBase-Compara
      Csp5_scaffold_00022.g1339 Caenorhabditis sinica From_analysis: WormBase-Compara
      FL83_00196 Caenorhabditis latens From_analysis: WormBase-Compara
      GCK72_024753 Caenorhabditis remanei From_analysis: WormBase-Compara
      OTIPU.nOt.2.0.1.g12888 Oscheius tipulae From_analysis: WormBase-Compara
      Pan_g19082 Panagrellus redivivus From_analysis: WormBase-Compara
      Pan_g23780 Panagrellus redivivus From_analysis: WormBase-Compara
      Pan_g23804 Panagrellus redivivus From_analysis: WormBase-Compara
      chrX_pilon.g19390 Caenorhabditis elegans From_analysis: WormBase-Compara
      WBGene00109151 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00273040 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00304265 Pristionchus pacificus From_analysis: WormBase-Compara
      WBGene00261681 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00261682 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00264550 Strongyloides ratti From_analysis: WormBase-Compara
      WBGene00291283 Trichuris muris From_analysis: WormBase-Compara
      WBGene00294632 Trichuris muris From_analysis: WormBase-Compara
      WBGene00294639 Trichuris muris From_analysis: WormBase-Compara
      WBGene00297515 Trichuris muris From_analysis: WormBase-Compara
      WBGene00297516 Trichuris muris From_analysis: WormBase-Compara
      WBGene00300323 Trichuris muris From_analysis: WormBase-Compara
      WBGene00300324 Trichuris muris From_analysis: WormBase-Compara
      SGD:S000002776 Saccharomyces cerevisiae From_analysis: EnsEMBL-Compara
            Inparanoid
            OMA
            OrthoInspector
            SonicParanoid
      FB:FBgn0086254 Drosophila melanogaster From_analysis: EnsEMBL-Compara
            Panther
            SonicParanoid
      ZFIN:ZDB-GENE-041210-132 Danio rerio From_analysis: EnsEMBL-Compara
            OMA
            Panther
      HGNC:381 Homo sapiens From_analysis: EnsEMBL-Compara
            OMA
            Panther
      HGNC:382 Homo sapiens From_analysis: EnsEMBL-Compara
            OMA
            Panther
      HGNC:37281 Homo sapiens From_analysis: EnsEMBL-Compara
            OMA
            Panther
      MGI:1353494 Mus musculus From_analysis: EnsEMBL-Compara
            OMA
            Panther
      MGI:101918 Mus musculus From_analysis: EnsEMBL-Compara
            OMA
            Panther
      MGI:107673 Mus musculus From_analysis: EnsEMBL-Compara
            OMA
            Panther
      MGI:1351662 Mus musculus From_analysis: EnsEMBL-Compara
            OMA
            Panther
      MGI:1915111 Mus musculus From_analysis: EnsEMBL-Compara
            OMA
            Panther
      MGI:1918111 Mus musculus From_analysis: EnsEMBL-Compara
            OMA
            Panther
      MGI:1933427 Mus musculus From_analysis: EnsEMBL-Compara
            OMA
            Panther
      MGI:1351661 Mus musculus From_analysis: EnsEMBL-Compara
            OMA
            Panther
      RGD:2092 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OMA
            Panther
      RGD:620257 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OMA
            Panther
      RGD:708475 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OMA
            Panther
      RGD:1308277 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OMA
            Panther
      RGD:1309599 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OMA
            Panther
      RGD:1306847 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OMA
            Panther
      RGD:1562954 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OMA
            Panther
      RGD:1359406 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OMA
            Panther
      RGD:1559604 Rattus norvegicus From_analysis: EnsEMBL-Compara
            OMA
            Panther
    Paralog (13)
    Structured_description: Automated_description: Predicted to enable alditol:NADP+ 1-oxidoreductase activity. Predicted to be located in cytosol. Expressed in germ line. Human ortholog(s) of this gene implicated in several diseases, including diabetic neuropathy; gastrointestinal system cancer (multiple); and type 2 diabetes mellitus. Is an ortholog of human AKR1B1 (aldo-keto reductase family 1 member B); AKR1B10 (aldo-keto reductase family 1 member B10); and AKR1B15 (aldo-keto reductase family 1 member B15). Paper_evidence: WBPaper00065943
          Curator_confirmed: WBPerson324
            WBPerson37462
          Inferred_automatically: This description was generated automatically by a script based on data from the WS291 version of WormBase
          Date_last_updated: 29 Nov 2023 00:00:00
  Disease_info: Potential_model: DOID:9352 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:381)
      DOID:2349 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:381)
      DOID:10534 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:381)
      DOID:8947 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:381)
      DOID:684 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:381)
      DOID:9743 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:381)
      DOID:83 Homo sapiens Inferred_automatically: Inferred by orthology to human genes with DO annotation (HGNC:381)
  Molecular_info: Corresponding_CDS: C07D8.6
    Corresponding_transcript: C07D8.6.1
    Other_sequence (101)
    Associated_feature: WBsf235923
  Experimental_info: RNAi_result: WBRNAi00092615 Inferred_automatically: RNAi_primary
      WBRNAi00010387 Inferred_automatically: RNAi_primary
      WBRNAi00039997 Inferred_automatically: RNAi_primary
      WBRNAi00061370 Inferred_automatically: RNAi_primary
      WBRNAi00028628 Inferred_automatically: RNAi_primary
      WBRNAi00007927 Inferred_automatically: RNAi_primary
    Expr_pattern: Expr4146
      Expr1018843
      Expr1036666
      Expr1144075
      Expr2000572
      Expr2018798
    Drives_construct: WBCnstr00028747
    Construct_product: WBCnstr00028747
    Microarray_results (20)
    Expression_cluster (199)
    Interaction (55)
  Map_info: Positive: Positive_clone: C07D8 Inferred_automatically: From sequence, transcript, pseudogene data
    Interpolated_map_position: X -1.75248
  Reference: WBPaper00028360
    WBPaper00028527
    WBPaper00029197
    WBPaper00038491
    WBPaper00055090
  Method: Gene