WormBase Tree Display for Gene: WBGene00015297
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| WBGene00015297 | SMap | S_parent | Sequence | C01F1 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | sco-1 | Person_evidence | WBPerson2601 | |||||
| Sequence_name | C01F1.2 | ||||||||
| Molecular_name | C01F1.2 | ||||||||
| C01F1.2.1 | |||||||||
| CE06743 | |||||||||
| Other_name | CELE_C01F1.2 | Accession_evidence | NDB | BX284602 | |||||
| Public_name | sco-1 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 28 May 2004 13:30:55 | WBPerson1971 | Event | Imported | Initial conversion from CDS class of stlace from WS125 | ||
| 2 | 18 Mar 2009 14:15:50 | WBPerson9133 | Name_change | CGC_name | sco-1 | ||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | sco | ||||||||
| Allele (22) | |||||||||
| Strain | WBStrain00037701 | ||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (12) | |||||||||
| Contained_in_operon | CEOP2120 | ||||||||
| Ortholog (34) | |||||||||
| Structured_description | Concise_description | sco-1 is orthologous to the human gene SCO (CYTOCHROME OXIDASE DEFICIENT, YEAST) HOMOLOG 1 (SCO1; OMIM:603644), which when mutated leads to early-onset hepatic failure; the SCO-1 protein is predicted to be mitochondrial with 68% accuracy. | Paper_evidence | WBPaper00004424 | |||||
| WBPaper00004637 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson1823 | |||||||||
| WBPerson567 | |||||||||
| Date_last_updated | 18 Mar 2009 00:00:00 | ||||||||
| Automated_description | Predicted to enable copper chaperone activity and copper ion binding activity. Predicted to be involved in mitochondrial cytochrome c oxidase assembly. Predicted to be located in mitochondrial inner membrane. Used to study mitochondrial metabolism disease. Human ortholog(s) of this gene implicated in hypertrophic cardiomyopathy; mitochondrial complex IV deficiency nuclear type 2; and myopia. Is an ortholog of human SCO1 (synthesis of cytochrome C oxidase 1). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Experimental_model | DOID:700 | Homo sapiens | Paper_evidence | WBPaper00064182 | ||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 12 Oct 2022 00:00:00 | ||||||||
| Potential_model | DOID:0070493 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10603) | |||||
| DOID:11830 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10604) | ||||||
| DOID:0080357 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10604) | ||||||
| DOID:11984 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10604) | ||||||
| DOID:3762 | Homo sapiens | Inferred_automatically | Inferred by orthology to human genes with DO annotation (HGNC:10603,HGNC:10604) | ||||||
| Models_disease_in_annotation | WBDOannot00001337 | ||||||||
| Molecular_info | Corresponding_CDS | C01F1.2 | |||||||
| Corresponding_transcript | C01F1.2.1 | ||||||||
| Other_sequence (56) | |||||||||
| Associated_feature | WBsf644095 | ||||||||
| WBsf981184 | |||||||||
| WBsf221103 | |||||||||
| Experimental_info | RNAi_result (23) | ||||||||
| Expr_pattern | Expr1021702 | ||||||||
| Expr1036551 | |||||||||
| Expr1143417 | |||||||||
| Expr2015645 | |||||||||
| Expr2033877 | |||||||||
| Microarray_results (20) | |||||||||
| Expression_cluster (87) | |||||||||
| Interaction (38) | |||||||||
| Map_info | Map | II | Position | -4.93285 | Error | 0.018941 | |||
| Positive | Positive_clone | C01F1 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00029435 | ||||||||
| WBPaper00033751 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00053317 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00059862 | |||||||||
| WBPaper00061547 | |||||||||
| WBPaper00062979 | |||||||||
| WBPaper00064182 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
